Shailesh Thirumaleshwar

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Candida albicans is the major cause of candidiasis. Better patient compliance and therapeutic efficacy can be achieved by utilizing herbal antifungal agent curcumin which is 2.5-fold more potent than fluconazole at inhibiting the adhesion of C. albicans. Curcumin–hydroxypropyl-β-cyclodextrin (HPβCD) was first developed to increase the solubility of(More)
The rationale behind present work was to formulate a novel cream containing microsponges of miconazole nitrate to provide prolonged release. By means of quasi-emulsion solvent diffusion method using Eudragit RS-100 with different drug-polymer ratios microsponges were prepared. In the direction of optimizing microsponge formulation, diverse factors that(More)
Present work was aimed at designing of phosphated cross-linked microspheres of bael fruit gum (BFG) by emulsification method using sodium-tri-meta phosphate as a cross-linking agent for treatment of colon cancer using 5-fluorouracil as model drug. Stirring speed was found to be 1,000 rpm for about 5 h to be optimal to obtain reproducible microspheres. It(More)
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