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Hsp27 functions as a negative regulator of cytochrome c-dependent activation of procaspase-3
This work demonstrates that heat-shock protein 27 (Hsp27) inhibits cytochrome c (cyt c)-dependent activation of cas-3 and defines a novel function for Hsp27, the first evidence that a heat shock protein represses cas- 3 activation.
Lidar observations of cirrus cloud near the tropical tropopause: general features
Experimental study of delamination and kerf geometry of carbon epoxy composite machined by abrasive water jet
The present article focuses on mechanism of delamination and kerf geometry in abrasive water jet machining of carbon epoxy composite. In the present study, four process parameters of abrasive water…
Standalone Photovoltaic Water Pumping System Using Induction Motor Drive With Reduced Sensors
- Bhim Singh, Utkarsh Sharma, Shailendra Kumar
- EngineeringIEEE transactions on industry applications
- 10 April 2018
The proposed control scheme makes the system inherently immune to the variation in the pump constant, and the prototype of PV-powered IMD emulating the pump characteristics is developed in the laboratory to examine the performance under different operating conditions.
Determining double-K fracture parameters of concrete for compact tension and wedge splitting tests using weight function
Concrete Fracture Models and Applications
Foreword.- Preface.- List of Symbols and Abbreviations.- Introduction to Fracture Mechanics of Concrete.- Fracture Mechanics of Concrete - State-of-the-Art Review.- Fracture Behavior of Concrete…
Experimental study on abrasive water jet machining of carbon epoxy composite
ABSTRACT Carbon epoxy composite material is widely used in various technological applications. Traditional machining of this material is difficult. This paper presents research work involved in…
Abrogation of the cell death response to oxidative stress by the c-Abl tyrosine kinase inhibitor STI571.
- Shailendra Kumar, N. Mishra, D. Raina, S. Saxena, D. Kufe
- BiologyMolecular Pharmacology
- 1 February 2003
It is shown that inhibition of c-Abl signaling by STI571 attenuates mitochondrial dysfunction and cell death in the cellular response to oxidative stress.
Regulation of Bcr-Abl-induced SAP kinase activity and transformation by the SHPTP1 protein tyrosine phosphatase
- Michaela Liedtke, P. Pandey, Shailendra Kumar, S. Kharbanda, D. Kufe
- Biology, ChemistryOncogene
- 15 October 1998
Findings indicate that SHPTP1 functions as a tumor suppressor in cells transformed by Bcr-Abl, and also decreases Bcr -Abl-dependent transformation of fibroblasts.