Shailendra Achawal

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Five cases of Chiari malformation associated with atlantoaxial dislocation are presented. A lateral plate and screw fixation was performed in all cases. Reversal foramen magnotomy was performed in three cases and two patients underwent the conventional posterior bony decompression for Chiari malformation. In an average postoperative follow-up period of 8(More)
We report a case of a previously healthy 23-year-old Somalian care assistant. She presented with a 4 month history of persistent occipital headaches associated with intermittent nausea and vomiting. Computed tomography and magnetic resonance imaging of the brain showed a large enhancing lesion in the right cerebellar hemisphere with surrounding ring(More)
In patients with glioblastoma multiforme (GBM), there is no consensus on the sequential use of two existing regimens: post-operative Gliadel implantation into the surgical cavity and concomitant temozolomide with radiotherapy followed by adjuvant temozolomide ('Stupp protocol'). NICE in the guideline TA121 (July 2007) could not pass any judgement on the(More)
The concurrent presence of multiple primary brain tumours with different histological characteristics is very rare. A case of dual intracranial benign tumours comprising pituitary adenoma and vestibular schwannoma is described. The aetiology and genetic association of these pathologies is explored and the literature of multiple intracranial tumours of(More)
A 38-year-old male was found to have a retropharyngeal pseudomeningocele along with C1 - C2 dislocation. Absence of any possible history, misleading circumstantial evidence and rarity of the entity made it impossible to diagnose the condition preoperatively. Concurrent medical problems dominated and the patient died. As a result, outcome of the(More)
OBJECTIVE To investigate whether expression of regulatory components of the cell division cycle can be used independently to predict survival and response to adjuvant therapy in glioblastomas. METHOD A tissue micro-array, constructed using glioblastomas (n = 66), was stained using antibodies against minichromosome maintenance protein-2 (Mcm-2), expressed(More)
A 73-year-old female with a history of metastatic melanoma presented with extensive intracranial subarachnoid haemorrhage. Cranial imaging failed to reveal any vascular anomaly or tumour. MRI of the neuroaxis revealed a melanoma metastasis at T10 with associated subarachnoid haemorrhage. We review the literature on this rare presentation of subarachnoid(More)
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