Shahid Ahmed Khan

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In this study, we evaluated the safety and pharmacodynamic effects of the Fc-inactivated anti-β-amyloid (anti-Aβ) monoclonal antibody GSK933776 in patients with mild Alzheimer’s disease and mild cognitive impairment. Aβ and tau levels were investigated in cerebrospinal fluid (CSF), and the relationship between Aβ levels and Aβ modulation in plasma was(More)
OBJECTIVE To assess the safety, tolerability, pharmacokinetics, and pharmacodynamics of the Fc-inactivated anti-β amyloid (Aβ) monoclonal antibody (mAb) GSK933776 in patients with mild Alzheimer's disease (AD) or mild cognitive impairment (MCI). METHODS This was a two-part, single blind, placebo-controlled, first-time-in-human (FTIH) study of single (n =(More)
The energy demand of residential end users has been so far largely uncontrollable and inelastic with respect to the power grid conditions. In this paper, we describe a scheme to solve multiple knapsack problems (MKP) using heuristic algorithms. Keeping total energy consumption of each household appliance under certain threshold with maximum benefit is(More)
In this paper, we introduce a generic architecture for demand side management (DSM) and use combined model of time of use tariff and inclined block rates. The problem formulation is carried via multiple knapsack and its solution is obtained via ant colony optimization (ACO). Simulation results show that the designed model for energy management achieves our(More)
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