Shagun K. Bhatia

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PURPOSE To describe the RPE morphometry of healthy human eyes regarding age and topographic location using modern computational methods with high accuracy and objectivity. We tested whether there were regional and age-related differences in RPE cell area and shape. METHODS Human cadaver donor eyes of varying ages were dissected, and the RPE flatmounts(More)
Previous studies of human retinal pigment epithelium (RPE) morphology found spatial differences in density: a high density of cells in the macula, decreasing peripherally. Because the RPE sheet is not perfectly regular, we anticipate that there will be differences between conditions and when and where damage is most likely to begin. The purpose of this(More)
Adult male fistulated crossbred cattle and buffalo, four each, were on rations with rations of nonprotein nitrogen to carbohydrates of 1:45, 1:37.5, and 1:30 and a control of no urea in a 4 x 4 Latin square switchover design. The influence of various test diets on enzymes assimilating ruminal ammonia was elucidated to find an optimum ratio of nonprotein(More)
We explored the potential protective effects of tauroursodeoxycholic acid (TUDCA) on cone photoreceptor survival in a model of rapid retinal degeneration, the ß-Pde6 (rd1) (rd1) mouse model. We injected two strains of rd1 mice (B6.C3-Pde6b (rd1) Hps4(le)/J and C57BL/6J-Pde6b (rd1-2)/J mice) daily from postnatal day (P) 6 to P21 with TUDCA or vehicle. At(More)
Two each adult male crossbred cattle and murrah buffalo were fed a diet of alfalfa hay, chopped wheat straw, and concentrate mixture. Total rumen transaminase activity of cattle was higher than that of buffalo. Rumen protozoal fractions showed higher total transaminase activity than bacterial fractions in both ruminant species. Besides generally studied(More)
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