Shafiq Ahmad Tariq

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Three new phloroglucinol type compounds Indigoferin-A (1), Indigoferin-B (2) and Indigoferin-C (3), along with a known compound β-sitosterol were isolated from the Indegofera gerardiana Wall. The structures of Indigoferin-A (1), Indigoferin-B (2), and Indigoferin-C (3) were deduced on the basis of spectroscopic techniques (EI-MS, HREI-MS, (1)H NMR, (13)C(More)
Joshanda is a polyherbal product that is commonly used in the treatment of cold and flu usually accompanied by fever. The present study was designed to scrutinize the antipyretic activity of a decoction of Joshanda and its total saponin and sterol contents in brewer's yeast induced febrile mice. The results revealed marked attenuation of induced pyrexia by(More)
The antibacterial, antifungal, acute cytotoxicity, phytotoxicity and insecticidal profile of the crude extract and various fractions of Indigofera gerardiana have been studied. Six bacterial and fungal strains were used, of which Samonella typhi and Microsporum canis were the most susceptible strains with MICs 0.37 mg/mL and 0.09 mg/mL, respectively. The(More)
The current study was aimed to scrutinize acetylcholinesterase (AchE) inhibitory profile of two antidepressants, diazepam and phenobarbitone. The experimental designed was based on Michaelis-Menten parameters (apparent Michaelis constant (aKm) and apparent maximum velocity (aVm)) that estimate inhibition (%) as well as the type of inhibition (mechanism).(More)
Diabetes mellitus is a major metabolic disorder affecting a huge population all over the world. The aim of the current study was to validate the folkloric use of Artemisia indica as an antidiabetic plant by using the isolated compound carnosol from the chloroform fraction of Artemisia indica in streptozotocin-induced diabetes mellitus in rats. The(More)
The goal of this study was to explore the aerial parts of Artemisia scoparia (crude extract, total flavonoid contents, and aqueous fraction) for protein denaturation potential. The crude extract provoked marked attenuation of thermal-induced denatured protein in a concentration-dependent manner with maximum inhibition of 54.05 μg/mL at 500 μg/mL and IC50 of(More)
The present study deals with the erythrocytic acetylcholinesterase inhibitory activity of paracetamol and chloroquine in an in vitro protocol using Michaelis Menten parameters (Apparent Michaelis Constant (aKm) and Apparent Maximum Velocity (aVm). Paracetamol showed marked inhibition of the erythrocytic acetylcholinesterase. The inhibitory values for aKm(More)
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