This study describes the preparation, biodistribution of 153Sm-DTPA-SPION after intravenous injection in rats.
MATERIALS AND METHODS
The chelator DTPA dianhydride was conjugated to SPION using a small modification of the well-known cyclic anhydride method. Conjugation was done at a 1: 4 (SPION:ccDTPA) molar ratio. Conjugation reaction was… (More)