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The BRAF mutation is useful for prediction of clinical recurrence in low‐risk patients with conventional papillary thyroid carcinoma
Background The activating BRAFV600E mutation is the most common genetic alteration reported in papillary thyroid carcinoma (PTC). While some reports suggest the BRAFV600E mutation is associated with… Expand
Expression of excision repair cross-complementation group 1 as predictive marker for nasopharyngeal cancer treated with concurrent chemoradiotherapy.
- Jong-mu Sun, M. Ahn, +9 authors K. Park
- International journal of radiation oncology…
- 1 July 2011
PURPOSE Cisplatin-based concurrent chemoradiotherapy is the standard treatment of nasopharyngeal cancer. The expression of excision repair cross-complementation group 1 (ERCC1) has been reported to… Expand
Prevention of VEGF-mediated microvascular permeability by C-peptide in diabetic mice.
AIMS Human C-peptide has a beneficial effect on the prevention of diabetic neuropathy, nephropathy, and vascular complications; however, its role in protection against increased vascular permeability… Expand
Papillary adenocarcinoma arising in a duplication of the cecum
Malignant carcinomatous change is a rare complication in an enteric duplication cyst, and papillary adenocarcinoma is especially unusual. We describe a papillary adenocarcinoma, arising from a… Expand
TuJ1 (class III beta-tubulin) expression suggests dynamic redistribution of follicular dendritic cells in lymphoid tissue.
- Seungkoo Lee, K. Choi, H. Ahn, K. Song, J. Choe, I. Lee
- Biology, Medicine
- European journal of cell biology
- 9 March 2005
Follicular dendritic cells (FDCs) play central roles in the B cell survival, proliferation, and differentiation into memory cells. Here, we show that TuJ1 (class III beta-tubulin) is expressed… Expand
Differential expression in normal-adenoma-carcinoma sequence suggests complex molecular carcinogenesis in colon.
The majority of colon cancers develop from pre-existing adenomas. We analyzed the expression profiles in the sequence of normal colon crypts, adenomas and early-stage carcinomas using microdissected… Expand
Cyclooxygenase-2 inhibitors modulate skin aging in a catalytic activity-independent manner
It has been proposed that the pro-inflammatory catalytic activity of cyclooxygenase-2 (COX-2) plays a key role in the aging process. However, it remains unclear whether the COX-2 activity is a causal… Expand
Expression profiling and subtype-specific expression of stomach cancer.
The expression profiling and molecular grouping of stomach cancers has been a challenging task because of their complexity and variation. We have analyzed gene expression profiles of 22 gastric… Expand
Malgun (clear) cell change in Helicobacter pylori gastritis reflects epithelial genomic damage and repair.
- J. Jang, Seungkoo Lee, +4 authors I. Lee
- Medicine, Biology
- The American journal of pathology
- 1 April 2003
Cancers may develop in the background of genomic instability with accumulated mutations. Helicobacter pylori gastritis is characterized by acute foveolitis of the proliferative zone, which is found… Expand
RNA sequencing identifies novel markers of non-small cell lung cancer.
INTRODUCTION The development of reliable gene expression profiling technology increasingly impacts our understanding of lung cancer biology. Here, we used RNA sequencing (RNA-Seq) to compare the… Expand