Learn More
Deguelin exhibits potent apoptotic and antiangiogenic activities in a variety of transformed cells and cancer cells. Deguelin also exhibits potent tumor suppressive effects in xenograft tumor models for many human cancers. Our initial studies confirmed that deguelin disrupts ATP binding to HSP90 and consequently induces destabilization of its client(More)
The paper presents a new memory-addressing scheme for the realization of low power FFT processors. The scheme is based on the minimization of coefficient access and the reduction of switching activity by modifying the butterfly sequence. Therefore, power consumption in the complex multiplier and memory is significantly saved.
The Hsp90 facilitates proper folding of signaling proteins associated with cancer progression, gaining attention as a target for therapeutic intervention. The natural rotenoid deguelin was identified as an Hsp90 inhibitor, but concerns about neurotoxicity have limited prospects for clinical development. In this study, we report progress on deguelin(More)
Network-on-Chip (NoC) based Multi-Processor System-on-Chip (MPSoC) architecture is a promising SoC design solution, offering high computational power with lots of flexibilities. However, finding the optimal MPSoC architecture configuration remains an enormous challenge due to its high structural complexity and functional diversity. In this paper, we(More)
This work presents a system architecture and effective co-verification methodologies for the IEEE 802.11a Medium Access Control (MAC) layer/Physical (PHY) layer implementation. The architecture modeling includes hardware/software partitioning of a total system based on timing measurements from the C/C++ and Verilog design, and analysis of real-time(More)