Seung Kyu Lee

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Ju-Kyeong Eo5
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Chang-Kyun Kim5
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4Se-Hwan Park
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2007
2016
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Burnup measurement of spent fuel assembly by CZT-based gamma-ray spectroscopy for input nuclear material accountancy of pyroprocessing
Input nuclear material accountancy is crucial for a pyroprocessing facility safeguards. Until a direct Pu measurement technique is established, an indirect method based on code calculations with burnup measurement and neutron counting for <sup>244</sup>Cm could be a practical option. Burnup can be determined by destructive analysis (DA) for final… (More)
Peptide deformylase inhibitors with retro-amide scaffold: synthesis and structure-activity relationships.
Peptide deformylase (PDF) is a metalloprotease catalyzing the removal of a formyl group from newly synthesized proteins. Thus inhibition of PDF activity is considered to be one of the most effective antibiotic strategies. Reported herein are the synthesis and structure-activity relationship studies of retro-amide inhibitors based on actinonin, a naturally… (More)
Peptide deformylase inhibitors with non-peptide scaffold: synthesis and structure-activity relationships.
Peptide deformylase (PDF), which removes the formyl group at the N-terminal methionine residue of nascent protein, has been recognized as a potent target for antibacterial therapy. We report herein the synthesis and structure-activity relationship studies of non-peptide PDF inhibitors.
Structures of Staphylococcus aureus peptide deformylase in complex with two classes of new inhibitors.
Peptide deformylase (PDF) catalyzes the removal of the formyl group from the N-terminal methionine residue in newly synthesized polypeptides, which is an essential process in bacteria. Four new inhibitors of PDF that belong to two different classes, hydroxamate/pseudopeptide compounds [PMT387 (7a) and PMT497] and reverse-hydroxamate/nonpeptide compounds… (More)
Fungi Isolated from Pine Wood Nematode, Its Vector Japanese Pine Sawyer, and the Nematode-Infected Japanese Black Pine Wood in Korea
Pine tree death caused by pine wood nematode (PWN) involves phoretic relationships between PWN and its vector Japanese pine sawyer beetle (JPS). In an effort to understand the diversity of fungi involved in PWN life cycle, a total of 176 fungal isolates were collected from PWNs, adults and larvae of JPS, PWN-diseased Japanese black pine that was cut down in… (More)
The rust fungus Gymnosporangium in Korea including two new species, G. monticola and G. unicorne.
A survey was conducted of the rust fungus Gymnosporangium in Korea. We recollected previously known species, namely Gymnosporangium asiaticum, G. clavariiforme, G. globosum, G. japonicum and G. yamadae. Gymnosporangium nidus-avis and G. sabinae are reported for the first time from Korea, and two new species, G. monticola sp. nov. and G. unicorne sp. nov.,… (More)
The structure of Staphylococcus aureus phosphopantetheine adenylyltransferase in complex with 3'-phosphoadenosine 5'-phosphosulfate reveals a new ligand-binding mode.
Bacterial phosphopantetheine adenylyltransferase (PPAT) catalyzes the penultimate step in the coenzyme A (CoA) biosynthetic pathway. It catalyzes the reversible transfer of an adenylyl group from ATP to 4'-phosphopantetheine (Ppant) to form dephospho-CoA (dPCoA) and pyrophosphate. Previous structural studies have revealed how several ligands are recognized… (More)
Development of prototype induced-fission-based Pu accountancy instrument for safeguards applications.
Prototype safeguards instrument for nuclear material accountancy (NMA) of uranium/transuranic (U/TRU) products that could be produced in a future advanced PWR fuel processing facility has been developed and characterized. This is a new, hybrid neutron measurement system based on fast neutron energy multiplication (FNEM) and passive neutron albedo reactivity… (More)
Effects of Water Stress on the Endophytic Fungal Communities of Pinus koraiensis Needles Infected by Cenangium ferruginosum
To examine the effects of water stress and Cenangium ferruginosum (CF) on the fungal endophytic community of needles of Pinus koraiensis (PK), fungal endophytes isolated from the needles of 5-year-old PK seedlings were compared before and after exposure to water stress conditions and artificial inoculation with CF ascospores. Artificial CF inoculation was… (More)
Comparison of New Simple Methods in Fabricating ZnS(Ag) Scintillators for Detecting Alpha Particles
The silver-activated zinc sulfide, ZnS(Ag), sensor to detect alpha-particles is normally fabricated by means of heat-melting or epoxy mixing spread. However, the fabrication process is very complicated so that it creates high costs and requires special high-tech equipment to manufacture the detector. For this reason, we have developed a new fabrication… (More)