Seul-I Lee

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Cultures of primary tumors are very useful as a personalized screening system for effective therapeutic options. We here describe an effective method of reproducing human primary colon tumors through primary culture and a mouse xenograft model. A total of 199 primary colon tumor cultures were successfully established under optimized conditions to enrich for(More)
BACKGROUND CKD-516 is a novel vascular disrupting agent that shuts down intratumoral blood flow. We therefore hypothesized that concomitant administration of CKD-516 would enhance the therapeutic efficacy of radiofrequency ablation (RFA) by reducing heat sink effects. We assessed the effects of the combination of CKD-516 and RFA in a rat orthotopic(More)
aKorea Advanced Institute of Science and Technology (KAIST), Daejeon 34141, Korea.; bKorea Electrotechnology Research Institute (KERI), Ansan 15588, Korea ; cMedical Research Institute, Gangneung Asan Hospital, 38, Bangdong-gil, Sacheon-myeon, Gangneung, Korea; dAsan Biomedical Research Institute, Asan Medical Center, University of Ulsan College of(More)
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