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Selectivity and Plasticity in a Sound-Evoked Male-Male Interaction in Drosophila
During courtship, many animals, including insects, birds, fish, and mammals, utilize acoustic signals to transmit information about species identity. Although auditory communication is crucial acrossExpand
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Transfected Rat cMOAT Is Functionally Expressed on the Apical Membrane in Madin-Darby Canine Kidney (MDCK) Cells
AbstractPurpose. The purpose of the present study is to investigate the expression of canalicular multispecific organic anion transporter (cMOAT) by its cDNA transfection in polarized Madin-DarbyExpand
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Development of novel steroid sulfatase inhibitors: II. TZS-8478 potently inhibits the growth of breast tumors in postmenopausal breast cancer model rats
In postmenopausal breast cancer tissue, steroid sulfatase (STS) activity is high and much estrone sulfate also exists; these facts reveal that estrone sulfate may be involved in the growth of breastExpand
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Effects of the novel orally active antiestrogen TZE-5323 on experimental endometriosis.
Danazol and gonadotropin-releasing hormone agonists which are used as therapeutic drugs for endometriosis, develop adverse reactions in association with their long-term use. The efficacy ofExpand
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Immunohistochemical analysis of ubiquilin‐1 in the human hippocampus: Association with neurofibrillary tangle pathology
This post mortem immunohistochemical study examined the localization and distribution of ubiquilin‐1 (UBL), a shuttle protein which interacts with ubiquitin and the proteasome, in the hippocampusExpand
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Development of Orthogonal Linear Separation Analysis (OLSA) to Decompose Drug Effects into Basic Components
Drugs have multiple, not single, effects. Decomposition of drug effects into basic components helps us to understand the pharmacological properties of a drug and contributes to drug discovery. WeExpand
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Severity of Depressive Symptoms and Volume of Superior Temporal Gyrus in People Who Visit a Memory Clinic Unaccompanied
Background/Aims: Depression and cognitive decline are reported to be interrelated. Depression of older adults with memory complaints who seek medical help have not been well documented. This studyExpand
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Orthogonal linear separation analysis: an approach to decompose the complex effects of a perturbagen
Drugs have multiple, not single, effects. Decomposition of drug effects into basic components helps us to understand the pharmacological properties of a drug and contributes to drug discovery. WeExpand
Role of MRP family proteins in the export of organic anion compounds from liver and intestine
MRP and cMOAT are the organic anion transporters involved in the efflux of organic anions from cells. We have already found two novel cDNA sequences (MLP-1 and -2: MRP like protein) which show highExpand