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- Publications
- Influence
Selectivity and Plasticity in a Sound-Evoked Male-Male Interaction in Drosophila
- Jeonghyeon Yoon, E. Matsuo, +6 authors A. Kamikouchi
- Biology, Medicine
- PloS one
- 24 September 2013
During courtship, many animals, including insects, birds, fish, and mammals, utilize acoustic signals to transmit information about species identity. Although auditory communication is crucial across… Expand
Transfected Rat cMOAT Is Functionally Expressed on the Apical Membrane in Madin-Darby Canine Kidney (MDCK) Cells
- Setsuo Kinoshita, H. Suzuki, K. Ito, K. Kume, T. Shimizu, Y. Sugiyama
- Biology, Medicine
- Pharmaceutical Research
- 1 December 1998
AbstractPurpose. The purpose of the present study is to investigate the expression of canalicular multispecific organic anion transporter (cMOAT) by its cDNA transfection in polarized Madin-Darby… Expand
Development of novel steroid sulfatase inhibitors: II. TZS-8478 potently inhibits the growth of breast tumors in postmenopausal breast cancer model rats
- T. Saito, Setsuo Kinoshita, T. Fujii, K. Bandoh, T. Horiuchi
- Chemistry, Medicine
- The Journal of Steroid Biochemistry and Molecular…
- 1 February 2004
In postmenopausal breast cancer tissue, steroid sulfatase (STS) activity is high and much estrone sulfate also exists; these facts reveal that estrone sulfate may be involved in the growth of breast… Expand
Effects of the novel orally active antiestrogen TZE-5323 on experimental endometriosis.
- T. Saito, M. Yoshizawa, +6 authors Naoyuki Koizumi
- Medicine, Chemistry
- Arzneimittel-Forschung
- 25 December 2011
Danazol and gonadotropin-releasing hormone agonists which are used as therapeutic drugs for endometriosis, develop adverse reactions in association with their long-term use. The efficacy of… Expand
Immunohistochemical analysis of ubiquilin‐1 in the human hippocampus: Association with neurofibrillary tangle pathology
- K. Mizukami, E. Abrahamson, +5 authors M. Ikonomovic
- Biology, Medicine
- Neuropathology : official journal of the Japanese…
- 1 February 2014
This post mortem immunohistochemical study examined the localization and distribution of ubiquilin‐1 (UBL), a shuttle protein which interacts with ubiquitin and the proteasome, in the hippocampus… Expand
Development of Orthogonal Linear Separation Analysis (OLSA) to Decompose Drug Effects into Basic Components
- T. Mizuno, Setsuo Kinoshita, T. Ito, S. Maedera, H. Kusuhara
- Chemistry, Medicine
- Scientific Reports
- 12 February 2019
Drugs have multiple, not single, effects. Decomposition of drug effects into basic components helps us to understand the pharmacological properties of a drug and contributes to drug discovery. We… Expand
Severity of Depressive Symptoms and Volume of Superior Temporal Gyrus in People Who Visit a Memory Clinic Unaccompanied
- Taiki Kambe, A. Yasuda, Setsuo Kinoshita, Masahiro Shigeta, T. Kinoshita
- Medicine
- Dementia and Geriatric Cognitive Disorders Extra
- 31 May 2018
Background/Aims: Depression and cognitive decline are reported to be interrelated. Depression of older adults with memory complaints who seek medical help have not been well documented. This study… Expand
Orthogonal linear separation analysis: an approach to decompose the complex effects of a perturbagen
- T. Mizuno, Setsuo Kinoshita, S. Maedera, T. Ito, H. Kusuhara
- Chemistry, Biology
- 3 August 2018
Drugs have multiple, not single, effects. Decomposition of drug effects into basic components helps us to understand the pharmacological properties of a drug and contributes to drug discovery. We… Expand
Role of MRP family proteins in the export of organic anion compounds from liver and intestine
- Tomoko Hirohashi, K. Ito, +8 authors Y. Sugiyama
- Biology
- 9 October 1997
MRP and cMOAT are the organic anion transporters involved in the efflux of organic anions from cells. We have already found two novel cDNA sequences (MLP-1 and -2: MRP like protein) which show high… Expand