Learn More
INTRODUCTION Embryo implantation is a complex process involving maternal hormonal changes, immune responses and maturational events in the embryo. A pregnancy could fail when these events are not synchronized. It is speculated that in women, an elevation of natural killer (NK) cells may have an effect on reproductive performance, and NK cell levels in blood(More)
BACKGROUND While live birth is the principal clinical outcome following in vitro fertilization (IVF) treatment, the number of eggs retrieved following ovarian stimulation is often used as a surrogate outcome in clinical practice and research. The aim of this study was to explore the association between egg number and live birth following IVF treatment and(More)
The effect of intramural fibroids without uterine cavity involvement on the outcome of IVF treatment: a systematic review and meta-analysis background: The influence of fibroids on fertility is poorly understood. Submucosal and intramural fibroids that distort the endo-metrial cavity have been associated with decreased pregnancy rates (PRs) following IVF(More)
BACKGROUND There are conflicting results on whether the rate of blastocyst development before freezing influences the outcome of frozen-thawed blastocyst transfers. METHODS We conducted a systematic review and meta-analysis of controlled studies to compare pregnancy outcomes following transfer of thawed blastocysts that were frozen either on Day 5 or Day(More)
BACKGROUND The main objective of individualization of treatment in IVF is to offer every single woman the best treatment tailored to her own unique characteristics, thus maximizing the chances of pregnancy and eliminating the iatrogenic and avoidable risks resulting from ovarian stimulation. Personalization of treatment in IVF should be based on the(More)
BACKGROUND The success rate of IVF treatment is low. A recent systematic review and meta-analysis found that the outcome of IVF treatment could be improved in patients who have experienced recurrent implantation failure if an outpatient hysteroscopy (OH) is performed before starting the new treatment cycle. However, the trials were of variable quality,(More)
STUDY QUESTION Is there a relationship between ovarian reserve, quantified as ovarian response to stimulation, and miscarriage rate following IVF treatment? SUMMARY ANSWER There is a strong association between the number of oocytes retrieved and miscarriage rate following IVF treatment, with the miscarriage rate decreasing with an increasing number of(More)
screening as an alternative to prenatal testing for Down syndrome: preferences of women undergoing in vitro fertilization/intracytoplasmic sperm injection treatment. High pregnancy rate after comprehensive chromosomal screening of blastocysts. Acupuncture and in vitro fertilization: updated meta-analysis Sir, We updated our previously published(More)
STUDY QUESTION Is there a relation between the number of oocytes retrieved following ovarian stimulation and obstetric outcomes of preterm birth (PTB) and low birthweight (LBW) following IVF treatment? SUMMARY ANSWER There is an increased risk of PTB (<37 weeks gestation) and LBW (<2500 g) following IVF in women with a high number (>20) of oocytes(More)
Increase in older women presenting as unexplained subfertility may explain overuse of in vitro fertilisation Sesh Kamal Sunkara subspecialist in reproductive medicine 1 , Srividya Seshadri subspecialist in reproductive medicine 2 1 Kamphuis and colleagues analysed the overuse of in vitro fertilisation (IVF) treatment, focusing on the newer indications. 1(More)
  • 1