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The epigenetic silencing of tumor suppressor genes is a common event during carcinogenesis, and often involves aberrant DNA methylation and histone modification of gene regulatory regions, resultingContinue Reading
  • F Bai, Serrine S. Lau, Terrence J. Monks
  • Chemistry, Medicine
  • Chemical research in toxicology
  • 1999 (First Publication: 1 December 1999)
  • Direct injection of either 3,4-(+/-)-methylenedioxymethamphetamine (MDMA) or 3,4-(+/-)-methylenedioxyamphetamine (MDA) into the brain fails to reproduce the serotonergic neurotoxicity seen followingContinue Reading
  • R T Miller, Serrine S. Lau, Terrence J. Monks
  • Chemistry, Medicine
  • Chemical research in toxicology
  • 1996
  • alpha-Methyldopamine (alpha-MeDA) is a metabolite of the serotonergic neurotoxicants 3,4-(+/-)-(methylenedioxy)amphetamine (MDA) and 3,4-(+/-)-(methylenedioxy)methamphetamine (MDMA). alpha-MeDAContinue Reading