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VEGF transiently disrupts gap junctional communication in endothelial cells.

• Sergio Suárez, Kurt Ballmer-Hofer
• Journal of cell science
• 2001

Vascular endothelial growth factor, VEGF, stimulates angiogenesis by directly acting on endothelial cells. The effects of VEGF are mediated by two tyrosine kinase receptors, VEGFR-1 (Flt-1) and… (More)

Synergy between tumor necrosis factor alpha and interleukin-1 in the induction of sickness behavior in mice.

• R-M. Bluthé, Marc Pawlowski, +4 authors Robert Dantzer
• Psychoneuroendocrinology
• 1994

Like interleukin-1, recombinant human tumor necrosis factor alpha (TNF alpha) has been found to decrease social exploration and induce weight loss in mice in a dose and time-dependent manner. The… (More)

Biotransformation of the diterpenes epicandicandiol and candicandiol by Mucor plumbeus.

• Braulio M. Fraga, Laura E. Alvarez, Sergio Suárez
• Journal of natural products
• 2003

The microbiological transformation of the diterpene epicandicandiol (1) with Mucor plumbeus gave foliol (3), sideritriol (5), and 7beta,16alpha,17,18-tetrahydroxy-ent-kaurane (7), while the… (More)

Signalling properties of an HIV-encoded angiogenic peptide mimicking vascular endothelial growth factor activity.

• Patrick Scheidegger, Wolfgang Weiglhofer, +5 authors Kurt Ballmer-Hofer
• The Biochemical journal
• 2001

HIV-1 expresses a multifunctional protein called TAT (trans-acting transcriptional activator), the function of which in vivo is tightly correlated with the incidence of Kaposi's sarcoma in AIDS… (More)

Selective GRB2 SH2 inhibitors as anti-Ras therapy.

• Brigitte Gay, Sergio Suárez, Giorgio Caravatti, Pascal Furet, Tanya K. Meyer, Joseph Schoepfer
• International journal of cancer
• 1999

Given the key role of Ras in the mitogenic signaling by receptor tyrosine kinases, several targets upstream of Ras may prove to be excellent targets for drugs in the treatment of cancer caused by… (More)

Effect of potent and selective inhibitors of the Grb2 SH2 domain on cell motility.

• Brigitte Gay, Sergio Suárez, +5 authors Joseph Schoepfer
• The Journal of biological chemistry
• 1999

Cell motility has been correlated both with oncogenic invasiveness and metastatic potential. The development of selective inhibitors of motility has thus great potential importance. Grb2 is a SH2/SH3… (More)

The microbiological transformation of 7alpha-hydroxy-ent-kaur-16-ene derivatives by Gibberella fujikuroi.

• Braulio M. Fraga, Carlo Bressa, Pedro Olmos Gonzalez, Ricardo Guillermo, M. Paula Gomez Hernandez, Sergio Suárez
• Phytochemistry
• 2007

The biotransformation of 7alpha-hydroxy-ent-kaur-16-ene (epi-candol A) by the fungus Gibberella fujikuroi gave 7alpha,16alpha,17-trihydroxy-ent-kaur-16-ene and a seco-ring B derivative, fujenoic… (More)

Plasmodium falciparum glycolipid synthesis: constant and variant molecules of isolates and of strains with differing knob and cytoadherence phenotype.

• James A. Sherwood, Steven L Spitalnik, Sergio Suárez, Kevin Marsh, Russell J. Howard
• The Journal of protozoology
• 1988

Plasmodium falciparum-infected erythrocytes were metabolically labeled with tritiated glucosamine. Lipid extracts were analyzed by high-performance thin-layer chromatography to compare labeled… (More)

The microbiological transformation of the diterpenes dehydroabietanol and teideadiol by Mucor plumbeus.

• Braulio M. Fraga, M. Paula Gomez Hernandez, Jose M Artega, Sergio Suárez
• Phytochemistry
• 2003

The microbiological transformation of dehydroabietanol (18-hydroxy-dehydroabietane) by Mucor plumbeus led to 2alpha,18-dihydroxy-abieta-8,11,13,15-tetraene, 2alpha,15-dihydroxy-dehydroabietanol,… (More)

Frequency of Kaposi's sarcoma in European AIDS patients who stayed in Africa.

• Danielle Seilhean, F Lazarini, Sergio Suárez, François Bricaire, J. J. Hauw
• AIDS
• 1997

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