Sergio Ferri

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We present the results of an investigation of the traditional ethnobotany and ethnomedicine of West Azerbaijan (Iran). In this region medicinal plants are often the only easily accessible health care alternative for most of the population in rural areas and in fact folk herbal medicine is the most used remedy to cure common diseases. In this paper we(More)
We determined the effects on nociceptive threshold and motor function of dynorphin-gene products, dynorphin A-(1-32) (DYN A-(1-32), DYN A-(1-8), DYN B and DYN B-29 and the non-opioid peptides somatostatin, neurotensin and salmon calcitonin (s-CT) after intrathecal administration in the rat. DYN A-(1-32) (25 nmol) produced maximal elevation of tail-flick(More)
We investigated the effects of sustained administration of cocaine on the regulation of prodynorphin gene expression in rat brain. Intracerebroventricular (i.c.v.) infusion of cocaine hydrochloride (30 micrograms/day) for 7 days, by means of osmotic minipumps, elicited a significant 35% decrease of prodynorphin mRNA levels in rat hypothalamus and increase(More)
The number of nerve cells in the myenteric plexus of a freshwater teleost (Pimelodus maculatus) was obtained with the aid of statistical methods. 1. The density of neurons/cm2 was the following: 91,142 in the duodenum; 93,133 in the ileum and 82,857 in the rectum. These 3 portions have not showed statistically significant differences. 2. The mean surface(More)
The regulation of neurotrophin (NT) secretion is critical for many aspects of NT-mediated neuronal plasticity. Neurons release NTs by activity-regulated secretion pathways, initiated either by neurotransmitters and/or by existing NTs by a positive-feedback mechanism. This process depends on calcium release from intracellular stores. Little is known,(More)
The effects of long-term administration of opioid agonists on the regulation of prodynorphin gene expression in rat brain were investigated. Chronic intracerebroventricular treatment with the synthetic opioid agonist acting on the kappa receptor, U-50,488H, and the classic mu agonist morphine markedly decreased prodynorphin mRNA levels in hypothalamus,(More)
Rats exposed to combined cold and restraint exhibited reduced paw oedema following an injection of carrageenin. Under the same experimental conditions, the local inflammation became fully evident when animals were pretreated with naloxone, 5 mg/kg, s.c. The same dose of the narcotic antagonist also increased the intensity of gastric damage in restrained,(More)