Sergio E. Quijada

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Most clinically demented elderly patients are found at autopsy to have Alzheimer's disease, multi-infarct dementia, Parkinson's disease, Pick's disease, or Creutzfeldt-Jakob disease. We studied 5 patients clinically characterized by late onset dementia whose brains showed no pathological evidence of Alzheimer's disease, or any other specific(More)
Immunocytochemical and quantitative immunochemical techniques were used to study the expression of Alz-50 antigen, ubiquitin and Tau in neurologic disorders characterized by the formation of filamentous neuronal inclusions. Alz-50, anti-ubiquitin and Tau-1 immunostained the intraneuronal neurofibrillary tangles and the neuritic component of plaques, both in(More)
Certain business objectives cannot be met without the interaction and communication between different systems. An interesting concept called system of systems (SoS), which aims to describe this interaction between systems has been gaining attention in the last few years. In this paper an extensive review of the literature is performed to capture the main(More)
System Dynamics, has been useful for a variety of disciplines; however, it has limitations in showing a geographical representation of the models under study. This paper proposes a methodology based on layered vectors which allows the use a city's census information to feed a Geographic Information System (GIS). The GIS objects implemented into System(More)
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