Sergey V Kovalev

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Twelve cardiac glycosides and aglycons were isolated from Strophanthus kombe seeds. Of these, eight were identified as cymarin, K-strophanthin-β, K-strophanthoside, periplocymarin, 17α-strophadogenin, erysimin (= helveticoside), erysimoside, and neoglucoerysimoside. Four glycosides, preliminarily designated Sk-x, Sk-y, Sk-z, and Sk-20, were new. Their(More)
The major portion of skin secretory peptidome of the European Tree frog Hyla arborea consists of short peptides from tryptophyllin family. It is known that b-ions of these peptides undergo head-to-tail cyclization, forming a ring that can open, resulting in several linear forms. As a result, the spectrum contains multiple ion series, thus complicating de(More)
Erysimum leptophyllum (M.B.), fam. Brassicaceae (Cruciferae), is a little-investigated source of cardiac glycosides of the cardenolide group. We have previously reported the presence of cardenolides in this plant [1]. In the seeds, by paper chromatography, we identified erysimoside, erycordin, and canescein. We have now continued the study of the seeds of(More)
Many species of the genus Crataegus are official and have been included in various pharmacopoeias. North American species of Crataegus have been cultivated since the 18th century. The work of I. A. Samylina was dedicated to the study of Baltic and Tadzhik species of Crataegus. She also investigated certain North American species [1, 2]. Both wild and(More)
Hyla arborea schelkownikowi is one of the leaf frog species inhabiting the southern territories of Russia and the former USSR. This frog species is a member of the Hylidae Rafinesque, 1815 batrachians family. The present study deals with the previously uninvestigated peptidome of the Hyla arborea schelkownikowi skin secretion. Nano-electrospray ionization(More)
We performed proteome mapping (PM), cataloging, and bioinformation analysis of protein lysates of human neural (CD133(+)) progenitor and stem cells (NPSCs) isolated from the olfactory sheath of a nose, multipotent mesenchymal (CD29(+), CD44(+), CD73(+), CD90(+), CD34(-)) stromal cells (MMSCs) isolated from human bone marrow, and tumor (CD133(+)) stem cells(More)
Videolaparoscopic appendectomy was carried out in 108 patients with acute destructive appendicitis complicated by peritonitis. Local peritonitis was noted in 65 patients, diffuse peritonitis in 33 patients, periappendicular abscess in 10 patients. Postoperative complications were observed in 6 (5.6%) patients. Nobody died. A comparison of results of(More)
The genus Lotus L. (Fabaceae) numbers up to 200 species, the majority of which is concentrated in Mediterranean countries [1]. Over 30 Lotus species grow in the CIS [2]; of these, 10 in Ukraine [3]. The plants are used in folk medicine as a wound-healer, emollient, analgesic, sedative, and general tonic [4]. Our goal was to study the flavonoid composition(More)