Sergey V. Kotov

Learn More
Objective. To investigate the possibility of using a bioengineering system, which includes an electroencephalograph and a personal computer with a software for synchronous data transmission, recognition and classification of EEG signals, development of directions for intended actions in real time in the combination with the hand exoskeleton (the(More)
The pathologic role of autoantibodies in autoimmune disease is widely accepted. Recently, we reported that anti-myelin basic protein (MBP) serum Abs from multiple sclerosis (MS) patients exhibit proteolytic activity toward the autoantigen. The aim of this study is to determine MBP epitopes specific for the autoantibodies in MS and compare these data with(More)
The recovery of disturbed functions was followed up for 1 year after ischemic stroke in 85 patients with atherosclerotic stenosis of internal carotid arteries. Fifty patients underwent carotid endarterectomy and 35 patients refused surgery. Somatic signs, neurological status measured with the NIH-NINDS, functional state (Barthel index), quality of life and(More)
AIM The analysis of fatal outcomes of myasthenic crisis in patients with myasthenia. MATERIAL AND METHODS The data on 19 patients with myastheniccrisis admitted at the Moscow Regional Research and Clinical Institute («MONIKI») over 12 years (1997-2009) have been summarized. RESULTS AND CONCLUSION There are more than 600 patients with myasthenia in the(More)
OBJECTIVE Vision impairment is one of the most typical characteristics of multiple sclerosis (MS). This pathology develops due to the lesions of optic nerves and optic tracts in the brain or eye movement dysfunction. Low contrast vision impairment is very frequent and early detected. We assessed low contrast non-color vision in patients with MS. MATERIAL(More)
Five hundreds and thirty-six patients, aged from 19 to 50 years, have been studied. Occipital lobe epilepsy (OLE) have been diagnosed in 22 (4,1%) of cases. The study included evaluation of anamnesis, clinical and neurological examination, routine EEG and/or video-EEG monitoring and MRI of the brain. Duration of the study was 1-5 years (on average 3 years).(More)
Results of annual comparative clinical research of the Russian biosimilar of beta-IFN - 1в at 122 patients with multiple sclerosis are presented. There were positive dynamics on EDSS scores in both groups (in the main group and group of control) in a year of treatment. There were positive dynamics in frequency of relapses in the main group (with 1.5 to 0.4(More)