Serge Simard

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BACKGROUND The prosthesis used for aortic valve replacement (AVR) can be too small in relation to body size, thus causing valve prosthesis-patient mismatch (PPM) and abnormally high transvalvular pressure gradients. This study examined if there is a relation between PPM and short-term mortality after operation. METHODS AND RESULTS The indexed valve(More)
p < 0.0002), as was the prevalence of diarrhea ( p < 0.01), vomiting ( p < 0.001), and bone pain ( p < 0.001). Greater benefits related to several aspects of life were reported after DS than DG ( p < 0.0001). The mean serum levels of ferritin, calcium, and vitamin A were higher ( p < 0.001), and parathyroid hormone was lower. The yearly revision rate for(More)
BACKGROUND To avoid ischemic hand complications, the percutaneous transradial approach is only performed in patients with patent hand collateral arteries, which is usually evaluated with the modified Allen's test (MAT). This qualitative test measures the time needed for maximal palmar blush after release of the ulnar artery compression with occlusive(More)
BACKGROUND AND OBJECTIVES By studying cardiometabolic risk factors in children born after maternal biliopancreatic diversion bariatric surgery (AMS) compared with those in children born before maternal surgery (BMS), we tested the hypothesis that significant maternal weight loss may modify obesity-related factors transmitted via the intrauterine(More)
BACKGROUND High tidal volumes in patients with acute respiratory distress syndrome and acute lung injury lead to ventilator-induced lung injury and increased mortality. We evaluated the impact of tidal volumes on cardiac surgery outcomes. METHODS We examined prospectively recorded data from 3,434 consecutive adult patients who underwent cardiac surgery.(More)
OBJECTIVES This study examined the association between silicosis and lung cancer in a systematic review (and meta-analysis) of the epidemiologic literature, with special reference to the methodological quality of observational studies. METHODS We searched Medline, Toxline, BIOSIS and Embase (1966-May 2004) for original articles published in any language(More)
PURPOSE To determine the effectiveness of a multicomponent clinical intervention to reduce pain in outpatients with cancer. METHODS AND MATERIALS Sixty-four patients were randomly assigned to receive either a clinical intervention including an information session, the use of a pain diary, and the possibility to contact a physician to adjust the pain(More)
The metabolic syndrome X, characterized by insulin resistance, dyslipidemia, hypertension, and a male, visceral distribution of adipose tissue, is associated with increased morbidity and mortality from several prevalent diseases, such as diabetes, cancers, myocardial infarction, and stroke. Because the liver has a central role in carbohydrate, lipid, and(More)
OBJECTIVE Our aim was to compare the prevalence of obesity in 172 children who were aged 2 to 18 years and born to 113 obese mothers (BMI: 31 +/- 9 kg/m2) with substantial weight loss after biliopancreatic bypass surgery with 45 same-age siblings who were born before maternal surgery (mothers' BMI: 48 +/- 8 kg/m2) and with current population standards. (More)
OBJECTIVES This study was designed to prospectively determine, in patients with an acute coronary syndrome, whether the inflammatory marker, C-reactive protein (CRP), measured at hospital admission, discharge, and 1 month later has incremental value to predict outcomes at 1 year. BACKGROUND The clinical utility of CRP measurements in patients with acute(More)