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  • Claudia Cartoni, Maria Eugenia Schininá, +9 authors Umberto Agrimi
  • Chemistry, Medicine
  • Journal of chromatography. B, Analytical…
  • 2007 (First Published: 1 April 2007)
  • The conversion of the cellular prion protein (PrP(C)) into a misfolded isoform (PrP(TSE)) that accumulates in the brain of affected individuals is the key feature of transmissible spongiformContinue Reading
  • Franco Cardone, Serena Principe, +12 authors Maurizio Pocchiari
  • Biology, Medicine
  • Biochemical and biophysical research…
  • 2014 (First Published: 1 November 2014)
  • Creutzfeldt-Jakob disease (CJD) is a neurodegenerative disorder characterized by the deposition of the pathological conformer (PrP(CJD)) of the host encoded cellular prion protein (PrP(C)). InContinue Reading
  • Serena Principe, Bruno Maras, Maria Eugenia Schininá, Maurizio Pocchiari, Franco Cardone
  • Medicine, Chemistry
  • Current opinion in drug discovery & development
  • 2008 (First Published: 1 September 2008)
  • Transmissible spongiform encephalopathies (TSEs), or prion diseases, are neurodegenerative disorders affecting both humans and animals. TSEs are caused by the infectious agent 'prion', which isContinue Reading