Serena Mulé

Learn More
BACKGROUND Impulsivity is elevated among people diagnosed with bipolar disorder, and recent evidence suggests that impulsivity can predict onset among those at risk for the disorder. Impulsivity, though, is a broad construct. OBJECTIVE The goal of this study was to examine whether some aspects of impulsivity are more correlated with risk for mania than(More)
In patients with schizophrenia who do not have an optimal response to clozapine, it remains unclear if there is an evidence base to support a second antipsychotic in combination with clozapine. The present systematic review was therefore carried out to determine the efficacy of various clozapine combination strategies with antipsychotics. Relevant studies(More)
BACKGROUND One third to two thirds of people with schizophrenia have persistent psychotic symptoms despite clozapine treatment. Under real-world circumstances, the need to provide effective therapeutic interventions to patients who do not have an optimal response to clozapine has been cited as the most common reason for simultaneously prescribing a second(More)
A practical clinical trial comparing haloperidol, risperidone, and olanzapine for the acute treatment of first-episode nonaffective psychosis. Q Are first and second generation antipsychotics equally effective and safe for people with first-episode non-affective psychosis? METHOD Design: Randomised controlled trial. Patients: 182 adults (15–60 years old;(More)
  • 1