Seong-Mi Choi

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Mesenchymal stem cells (MSCs) are multipotent adult stem cells that can be isolated from various fetal and adult tissues. Over the fast decades, their multipotency, tissue reparative action, homing ability and immunoregulatory properties raised a great expectation in the field of stem cell and regenerative medicine that is being actively translated in a(More)
Recently, cell-based therapy has been highlighted as an alternative to treating ischemic brain damage in stroke patients. The present study addresses the therapeutic potential of polysialic acid-neural cell adhesion molecule (PSA-NCAM)-positive neural precursor cells (NPCPSA-NCAM+) derived from human embryonic stem cells (hESCs) in a rat stroke model with(More)
Adiponectin, one of the most abundant plasma protein produced in adipose tissue, has been shown to be decreased in the plasma of patients with various types of cancer suggesting that adiponectin may be involved in the pathogenesis of tumor progression. In addition, studies have shown that this adipokine exhibit a suppressive effect on different types of(More)
There have been concerns that systemic corticosteroid use is associated with pregnancy-induced hypertension (PIH) and diabetes mellitus. However, the relationship between inhaled corticosteroids (ICSs) and the risk of PIH has not been fully examined, and there was no study investigating the association between ICS use and the development of gestational(More)
Transplantation of mesenchymal stem cells (MSCs) was reported to improve functional outcomes in a rat model of ischemic stroke, and subsequent studies suggest that MSC-derived microvesicles (MVs) can replace the beneficial effects of MSCs. Here, we evaluated three different MSC-derived MVs, including MVs from untreated MSCs (MSC-MVs), MVs from MSCs treated(More)
OBJECTIVES Few nationwide population-based studies have examined the burden of asthma during pregnancy. Here, we investigated the burden and medical treatment of asthma during pregnancy requiring healthcare utilisation in South Korea. DESIGN Cohort study. SETTING Nationwide insurance claims database. PARTICIPANTS A total of 1,306,281 pregnant women(More)
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