Seong Hwan Park

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Owing to its tumor tropism and prolonged transgene expression, mesenchymal stem cell (MSC) has been considered as an ideal delivery vehicle for cancer gene therapies or therapeutic vaccines. In this study, we demonstrated that intratumoral (i.t.) injection of MSCs expressing modified interleukin-12 (MSCs/IL-12M) exhibited stronger tumor-specific T-cell(More)
Most of human dirofilariasis are pulmonary or subcutaneous infections, but there have been a few reports of human dirofilariasis in unusual sites, such as large vessels, mesentery, peritoneal cavity, and spermatic cord. We present the first case of human hepatic dirofilariasis, which was surgically diagnosed. A 39-year-old man without any evidence of(More)
Voltage dependent calcium channel (VDCC) mediates the influx of free calcium ions that acts as a signal transducer. The beta 3 subunit of the VDCC regulates the activation (opening) and inactivation (closing) kinetics through phosphorylation/dephosphorylation. We isolated a genomic clone of the human VDCC beta 3 subunit from a human genomic DNA library(More)
Blowflies, especially species belonging to the subfamily Luciliinae, are the first insects to lay eggs on corpses in Korea. Fast and accurate species identification has been a key task for forensic entomologists. Because conventional morphologic identification methods have many limitations with respect to forensic practice, molecular methods have been(More)
Vomeronasal sensitivity is important for detecting intraspecific pheromonal cues as well as environmental odorants and is involved in mating, social interaction, and other daily activities of many vertebrates. Two large families of seven-transmembrane G-protein-coupled receptors, V1rs and V2rs, bind to various ligands to initiate vomeronasal signal(More)
Identifying species of insects used to estimate postmortem interval (PMI) is a major subject in forensic entomology. Because forensic insect specimens are morphologically uniform and are obtained at various developmental stages, DNA markers are greatly needed. To develop new autosomal DNA markers to identify species, partial genomic sequences of the bicoid(More)
Identification of insect species is an important task in forensic entomology. For more convenient species identification, the nucleotide sequences of cytochrome c oxidase subunit I (COI) gene have been widely utilized. We analyzed full-length COI nucleotide sequences of 10 Muscidae and 6 Sarcophagidae fly species collected in Korea. After DNA extraction(More)
Thirty-eight species belonging to 15 genera of the family Sarcophagidae were found so far in Korea. The description, locality in Korea, distribution and bionomics of these species are given in this paper. The fifth sternite, forceps and genitalia of these male flies are illustrated. The key to the species of sarcophagid flies in Korea are also presented.
Forty species belonging to 14 genera of the family Muscidae were found so far in Korea. They are described in this paper and 5th sternites, forceps and male genitalia are illustrated. Eleven species recorded by Kobayashi (1918-1940) and 16 species by Hori (1952) were revised and redescribed in this paper. The key to the species of the muscid flies in Korea(More)
We investigate the effects of time delayed interactions in the network of neural oscillators. We perform the stability analysis in the vicinity of a synchronized state at vanishing time delay and present a related phase diagram. In the simulations it is shown that time delay induces various phenomena such as clustering where the system is spontaneously(More)