Seong Hee Choi

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The aim of this study was to measure the shear modulus of the vocal fold in a human hemilarynx, such that the data can be related to direction of applied stress and anatomical context. Dynamic spring rate data were collected using a modified linear skin rheometer using human hemilarynges, and converted to estimated shear modulus via application of a simple(More)
Involvement of additional hormones other than estrogen in the control of vitellogenin (Vg) synthesis has been suggested in fish. However, no satisfactory explanation on the mechanism of the action of these hormones has been reported. In this study, we have exploited the possibility of androgen receptor mediation during the androgen action on the pathway of(More)
BACKGROUND AND OBJECTIVES People usually converse in real-life background noise. They experience more difficulty understanding speech in noise than in a quiet environment. The present study investigated how speech recognition in real-life background noise is affected by the type of noise, signal-to-noise ratio (SNR), and age. SUBJECTS AND METHODS Eighteen(More)
The primary site of lesion induced by noise exposure is the hair cells in the organ of Corti and the primary neural degeneration occurs in synaptic terminals of cochlear nerve fibers and spiral ganglion cells. The cellular basis of noise-induced hearing loss is oxidative stress, which refers to a severe disruption in the balance between the production of(More)
OBJECTIVE To investigate the effect of vocal fold injury location on vibratory amplitude and lateral phase difference. STUDY DESIGN Repeated measures with each excised canine larynx serving as own control. SETTING Basic science study conducted in university laboratory. METHODS Vocal fold vibration of excised canine larynges was recorded with a(More)
Gene expressions of cytochrome P4501A (CYP1A), aryl hydrocarbon receptor (AhR) and vitellogenin (Vg) by endocrine disruptors, benzo[α]pyrene (B[a]P) and tributyltin (TBT) were examined in cultured eel hepatocytes which were isolated from eels treated previously with B[a]P (10 mg/kg) or estradiol-17β (20 mg/kg) in vivo, and the relationship between CYP1A,(More)
OBJECTIVE/HYPOTHESIS Acoustic analysis is a commonly used method for quantitatively measuring vocal fold function. Voice signals are analyzed by selecting a waveform segment and using various algorithms to arrive at parameters such as jitter, shimmer, and signal-to-noise ratio (SNR). Accurate and reliable methods for selecting a representative vowel segment(More)
(2011) Cross-sample validation provides enhanced proteome coverage in rat vocal fold mucosa. PLoS ONE 6(3): e17754. Table S1. Functional classification of proteins identified by LC-MS/MS. Data are drawn from three independent vocal fold mucosa samples using an identification threshold based on a 1% estimated false positive rate, removal of global single(More)
The vocal fold mucosa is a biomechanically unique tissue comprised of a densely cellular epithelium, superficial to an extracellular matrix (ECM)-rich lamina propria. Such ECM-rich tissues are challenging to analyze using proteomic assays, primarily due to extensive crosslinking and glycosylation of the majority of high M(r) ECM proteins. In this study, we(More)
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