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Nucleic acid-based aptamers offer many potential advantages relative to antibodies and other protein-based affinity reagents, including facile chemical synthesis, reversible folding, improved thermal stability and lower cost. However, their selection requires significant time and resources and selections often fail to yield molecules with affinities(More)
A marine bacterial strain, designated A71(T), was isolated from marine algae collected from the South Sea, Republic of Korea. Phylogenetic analysis based on 16S rRNA gene sequences indicated that strain A71(T) belonged to the family Flavobacteriaceae and was closely related to Aequorivita antarctica SW49(T) (96.5 % sequence similarity). Cells of strain(More)
A non-motile and rod shaped bacterium, designated strain B1T, was isolated from forest soil at Mt. Baekwoon, Republic of Korea. Cells were Gram-negative, catalase-positive, and oxidase-negative. The major fatty acids were 9-octadecenoic acid (C18:1 ω9c; 42%) and hexadecanoic acid (C16:0; 25.9%) and summed feature 3 (comprising iso-C15:0 2-OH and/or C16:1(More)
The generation of nucleic acid aptamers with high affinity typically entails a time-consuming, iterative process of binding, separation, and amplification. It would therefore be beneficial to develop an efficient selection strategy that can generate these high-quality aptamers rapidly, economically, and reproducibly. Toward this goal, we have developed a(More)
Albert Einstein is reputed to have once said, “if you can’t explain it to a six-year-old, then you don’t understand it yourself.” The precision and conciseness of Julie Schwartz Gottman and John Gottman’s book, 10 Principles for Doing Effective Couples Therapy, is an excellent demonstration of this concept. The book, which reflects the latest product of the(More)
In this paper, we present our compiler infrastructure, called Jaguar for Java reconfigurable computing. The Jaguar compiler translates compiled Java methods, i.e. sequence of bytecodes into Verilog synthesizable code modules with exploiting the maximum operational parallelism in applications. Our compiler infrastructure consists of two major components: One(More)
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