Seon G. Chang

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Allelic deletion or transcriptional silencing of RASSF1, a putative tumor suppressor at 3p21.3, has been found in a considerable proportion of lung, breast, and ovarian cancers. In this study, we analyzed the expression and mutation status of three RASSF1 isoforms (-A, -B, and -C) in 55 primary bladder carcinomas and 10 bladder and prostate cancer cell(More)
p63, a recently identified member of the p53 gene family, encodes multiple products with transactivating, death-inducing, and dominant-negative activities. To explore the penetrance of p63 in bladder carcinogenesis, we performed expression and mutation analyses of two major isotypes, TAp63 and deltaNp63, in 63 bladder specimens. In 12 normal tissues, TAp63(More)
p73, a member of the p53 family at 1p36.3, has been demonstrated to be expressed monoallelically and induce apoptosis or G1 arrest of the cell cycle. To explore the candidacy of p73 as a suppressor in bladder tumorigenesis, we examined expression level, allelic origin, and mutation of p73 mRNA in 45 primary bladder carcinomas. Quantitative PCR analysis(More)
– Location management is important to effectively keep track of mobile terminals with reduced signal flows and database queries. Even though dynamic location management strategies are known to show good performance, we in this paper consider the static location management strategy which is easy to implement. A system with single home location register and(More)
Location management is important to effectively keep track of mobile terminals with reduced signal flows and database queries. A system with single home location register and pointer forwarding is assumed. A mobile terminal is assumed to have memory to store the IDs of visitor location registers (VLRs) each of which has the forwarding pointer to identify(More)
Purpose Asthma is a chronic disease increasingly found in children. In order to find more economical and efficient alternatives to treat pediatric asthma, the Bureau of National Health Insurance of Taiwan launched the Traditional Chinese Medicine Holistic Treatment Program (TCMHTP). Based on the data collected during the program, we evaluated the effect of(More)
The personal communication service (PCS) is a system that aims to allow for communication anywhere in the world. PCS networks support mobile terminals (MTs) that are free to travel, and the network access point of an MT changes as it moves around the network coverage area. As a result, location management is important to effectively keep track of mobile(More)
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