Seok Jong Chang

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AIM To investigate the effects of Korea red ginseng (KRG) on the cerebral perfusion rate in the rats and the generation of superoxide anion in the endothelial cells. METHODS The cerebral perfusion rate was measured using laser-doppler flowmetry before and after the administration of crude saponin (CS) and saponin-free fraction (SFF) of KRG in the(More)
Ulmus davidiana var. japonica Rehder (Urticales: Ulmaceae) (UD) is a tree widespread in northeast Asia. It is traditionally used for anticancer and anti-inflammatory therapy. The present study investigated the effect of an ethanol extract of UD on vascular tension and its underlying mechanism in rats. The dried root bark of UD was ground and extracted with(More)
The effect of maternal vitamin B-6 deficiency on the morphological changes in the dendritic growth of Purkinje cells of progeny was studied at four different ages (12, 15, 21, and 50 days) of postnatal development. By day 10, rat pups in the deficient groups (0.6 or 1.0 mg pyridoxine . HCl/kg diet) began to show gross neurological symptoms of the deficiency(More)
Bladder cancer (BCa) is one of the most common urothelial cancers with still noticeable incidence rate. Early detection of BCa is highly correlated with successful therapeutic outcomes. We previously showed that apurinic/apyrimidinic endonuclease 1/redox factor-1 (APE1/Ref-1) was expressed at an increased level in the serum of BCa patients when compared to(More)
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