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In this paper, extensive study of ring-opening polymerization ε-caprolactone (ε-CL) using lipase Novozym 435 as catalyst in flask level and reactor level were conducted. The polymerization rates increase with an increase in time up to 4 h after which there has been a steep decrease for all temperature from 50 to 100 °C in the flask level. The conclusion out… (More)