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Mucus-PVPA (mucus Phospholipid Vesicle-based Permeation Assay): An artificial permeability tool for drug screening and formulation development.
The mucus layer covering all mucosal surfaces in our body is the first barrier encountered by drugs before their potential absorption through epithelial tissues, and could thus affect the drugs'Expand
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Curcumin-In-Deformable Liposomes-In-Chitosan-Hydrogel as a Novel Wound Dressing
A liposomes-in-hydrogel system as an advanced wound dressing for dermal delivery of curcumin was proposed for improved chronic wound therapy. Curcumin, a multitargeting poorly soluble activeExpand
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Release Problems for Nifedipine in the Presence of Soluplus
Nifedipine/soluplus co-precipitates were prepared at 1:9 and 1:1 weight ratios, using the solvent method, with the aim to obtain an improvement of the drug release. The release, though acceleratedExpand
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Liposomes augment biological benefits of curcumin for multitargeted skin therapy.
Curcumin, a multi-targeting pharmacologically active compound, is a promising molecule for the treatment of skin inflammation and infection in chronic wounds. However, its hydrophobic nature remainsExpand
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The isolated perfused human skin flap model: A missing link in skin penetration studies?
&NA; Development of effective (trans)dermal drug delivery systems requires reliable skin models to evaluate skin drug penetration. The isolated perfused human skin flap remains metabolically activeExpand
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Going skin deep: A direct comparison of penetration potential of lipid‐based nanovesicles on the isolated perfused human skin flap model
Graphical abstract Figure. No Caption available. ABSTRACT Phospholipid‐based nanocarriers are attractive drug carriers for improved local skin therapy. In the present study, the recently developedExpand
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Deformable liposomes for skin therapy with human epidermal growth factor: The effect of liposomal surface charge
&NA; The topical administration of exogenous human epidermal growth factor (hEGF) is a promising approach for improved chronic wound therapy. To develop therapeutically superior hEGF formulation, weExpand
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