Seheli Parveen

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Quaternization of the nitrogen atom of 2-amino-4-chlorophenyl phenyl sulfide analogues of chlorpromazine improved inhibition approximately 40-fold (3',4'-dichlorobenzyl-[5-chloro-2-phenylsulfanyl-phenylamino)-propyl]-dimethylammonium chloride inhibited trypanothione reductase from Trypanosoma cruzi with a linear competitive Ki value of 1.7 +/- 0.2 microM).(More)
Cholera toxin and other bacterial toxins can induce electrogenic chloride (Cl) secretion in the small intestine resulting in secretory diarrhoea, when the colonic water reabsorption capacity is overwhelmed. The mechanism underlying this phenomena is that, these toxins increase intracellular cGMP and/or cAMP level through activation of guanylyl and adenylyl(More)
The objective of this study was to observe the drug interaction between levofloxacin and omeprazole using urinary excretion data. Levofloxacin tablet and omeprazole capsule were administered separately as well as in combination in fasting condition with a wash out period of two weeks after each administration. Urine was collected at different time intervals(More)
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