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- Seema Nanda, Helen Joy Moore, Suzanne Lenhart
- Mathematical biosciences
- 2007

We consider a mathematical model of drug therapy for chronic myelogenous leukemia for an individual patient over a fixed time horizon. The disease dynamics are given by a system of ordinary differential equations that describe the interaction between naive T cells, effector T cells and leukemic cancer cells in a hypothetical patient. We introduce two drug… (More)

- Seema Nanda
- 2008

We study the size of connected components of random nearestneighbor graphs with vertex set the points of a homogeneous Poisson point process in R. The connectivity function is shown to decay superexponentially, and we identify the exact exponent. From this we also obtain the decay rate of the maximal number of points of a path through the origin. We define… (More)

B cell chronic lymphocytic leukemia (B-CLL) is known to have substantial clinical heterogeneity. There is no cure, but treatments allow for disease management. However, the wide range of clinical courses experienced by B-CLL patients makes prognosis and hence treatment a significant challenge. In an attempt to study disease progression across different… (More)

- Elissa J. Schwartz, Seema Nanda, Robert H. Mealey
- Journal of virology
- 2015

Lentivirus escape from neutralizing antibodies (NAbs) is not well understood. In this work, we quantified antibody escape of a lentivirus, using antibody escape data from horses infected with equine infectious anemia virus. We calculated antibody blocking rates of wild-type virus, fitness costs of mutant virus, and growth rates of both viruses. These… (More)

We study the size of connected components of random nearest-neighbor graphs with vertex set the points of a homogeneous Poisson point process in Rd . The connectivity function is shown to decay superexponentially, and we identify the exact exponent. From this we also obtain the decay rate of the maximal number of points of a path through the origin. We… (More)

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