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We consider a mathematical model of drug therapy for chronic myelogenous leukemia for an individual patient over a fixed time horizon. The disease dynamics are given by a system of ordinary differential equations that describe the interaction between naive T cells, effector T cells and leukemic cancer cells in a hypothetical patient. We introduce two drug… (More)

- Iva Kozakova, Ronald Meester, Seema Nanda
- 2008

We study the size of connected components of random nearest-neighbor graphs with vertex set the points of a homogeneous Poisson point process in R d. The connectivity function is shown to decay superexponentially, and we identify the exact exponent. From this we also obtain the decay rate of the maximal number of points of a path through the origin. We… (More)

- Seema Nanda, Lisette Depillis, Ami Radunskaya
- 2013

B cell chronic lymphocytic leukemia (B-CLL) is known to have substantial clinical heterogeneity. There is no cure, but treatments allow for disease management. However, the wide range of clinical courses experienced by B-CLL patients makes prognosis and hence treatment a significant challenge. In an attempt to study disease progression across different… (More)

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