Sebastian Willert

Learn More
The utilization of VH gene families is severely biased during fetal development, such that D-region proximal VH genes are overrepresented. After birth the VH repertoire becomes more equally representative of the total inherited set of functional VH genes. To investigate the extent of this normalization process, we have determined the relative utilization of(More)
 A 40-year-old patient with low-grade B-NHL developed a generalized macular-papular rash following the first cycle of fludarabine treatment which progressed to a complete epidermal necrolysis following the second cycle. Clinical symptoms and the results of the direct and indirect immunofluorescence were consistent with a mucocutaneous autoimmune syndrome(More)
In previous studies, we showed that lacrimal gland acini express three isoforms of protein kinase C (PKC): PKCα,-δ, and -ε. In the present study, we report the identification of two other PKC isoforms, namely PKCμ and -ι/λ. Using immunofluorescence techniques, we showed that these isoforms are differentially located. PKCα and -μ showed the most prominent(More)
We describe implementation aspects and performance results of a novel general signaling protocol for the Internet the cross-application signaling protocol (CASP). There has been much debate on the applicability of RSVP as a general signaling protocol for the Internet, particularly with respect to its modularity, complexity, security and mobility support.(More)
Signaling has become necessary for allowing IP-based networks to manage states in network nodes. However, existing protocols cannot deliver desired signaling services needed for large-scale deployment. The Cross-Application Signaling Protocol (CASP), a general-purpose signaling protocol, introduces a new approach to overcome the limitations of these(More)
In this report, we describe implementation aspects and performance results of a novel general signaling protocol for the Internet, the Cross-Application Signaling Protocol (CASP). Much debate exists about the applicability of RSVP as a general signaling protocol in the Internet, particularly for its modularity, complexity, security and mobility support.(More)
  • 1