Sebastian Wiberg

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BACKGROUND Attenuating the neurological damage occurring after out-of-hospital cardiac arrest is an ongoing research effort. This dual-centre study investigates the neuroprotective effects of the glucagon-like-peptide-1 analogue Exenatide administered within 4 hours from the return of spontaneous circulation to comatose patients resuscitated from(More)
OBJECTIVES This study sought to determine clinical, procedural, and treatment factors associated with acute stent thrombosis (AST) in the EUROMAX (European Ambulance Acute Coronary Syndrome Angiography) trial. BACKGROUND Bivalirudin started during transport for primary percutaneous coronary intervention (PCI) for ST-segment elevation myocardial infarction(More)
Ultrasound is sometimes employed as an alternative technique to phlebography in the diagnosis of deep venous thromboses (DVT). To evaluate the efficacy of ultrasound, 74 patients suspected of DVT in the lower limbs were examined with both ultrasound and phlebography. The results indicate that positive reports following ultrasound examination are reliable(More)
BACKGROUND In-hospital mortality in comatose patients resuscitated from out-of-hospital cardiac arrest (OHCA) is ≈50%. In OHCA patients, the leading cause of death is neurological injury secondary to ischemia and reperfusion. Glucagon-like peptide-1 analogs are approved for type 2 diabetes mellitus; preclinical and clinical data have suggested their(More)
BACKGROUND The incidence of cardiogenic shock (CS) in patients with ST-segment elevation myocardial infarction (STEMI) is as high as 10%. The majority of patients are thought to develop CS after admission (late CS), but the incidence in a contemporary STEMI cohort admitted for primary percutaneous intervention remains unknown. AIM The aim of this study(More)
BACKGROUND Prediction of neurological outcome is a crucial part of post cardiac arrest care and prediction in patients remaining unconscious and/or sedated after rewarming from targeted temperature management (TTM) remains difficult. Current guidelines suggest the use of serial measurements of the biomarker neuron-specific enolase (NSE) in combination with(More)
Circulation. 2017;135:e1044–e1045. DOI: 10.1161/CIRCULATIONAHA.117.027774 e1044 Sebastian Wiberg, MD Christian Hassager, MD, DMSc Jesper Kjaergaard, MD, PhD, DMSc In Response: We appreciate the interest of Ma and colleagues in our article reporting the neuroprotective effects of the glucagon-like peptide-1 analog exenatide after out-ofhospital cardiac(More)
OBJECTIVES Carotid artery stenosis (CAS) and vertebral artery stenosis (VAS) are associated with cerebral infarction after coronary artery bypass graft surgery (CABG). It remains unclear whether this association is causal. We investigated the associations between neurologically asymptomatic CAS and VAS and the occurrence of subclinical cerebral lesions(More)
This study reports the prevalence and prognostic impact of right bundle branch block (RBBB) and left bundle branch block (LBBB) in the admission electrocardiogram (ECG) of comatose survivors of out-of-hospital cardiac arrest (OHCA). The present study is part of the predefined electrocardiographic substudy of the prospective randomized target temperature(More)