Sebastian W. Schmitt

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Brain transcriptome and connectome maps are being generated, but an equivalent effort on the proteome is currently lacking. We performed high-resolution mass spectrometry-based proteomics for in-depth analysis of the mouse brain and its major brain regions and cell types. Comparisons of the 12,934 identified proteins in oligodendrocytes, astrocytes,(More)
Rapid conduction of nerve impulses requires coating of axons by myelin sheaths, which are lipid-rich and multilamellar membrane stacks. The lipid composition of myelin varies significantly from other biological membranes. Studies in mutant mice targeting various lipid biosynthesis pathways have shown that myelinating glia have a remarkable capacity to(More)
The fovea centralis is a closely-packed vertical array of inverted-cone photoreceptor cells located in the retina that is responsible for high acuity binocular vision. The cones are operational in well-lit environments and are responsible for trapping the impinging illumination. We present the vertical light-funnel silicon array as a light-trapping(More)
Supplementary information S1: SEM micrographs of four SiNCs (tilt 70°) and one SiNW (tilt 45°) fabricated by cryogenic RIE with SF6 and O2 chemistry (scale bar is 1µm). Masking is performed with silica spheres (diameter 1µm). Different shapes can be realized by the adjustment of O2 concentration in the plasma that results in a different amount of under(More)
We investigate the trade-off between the robustness against random and targeted removal of nodes from a network. To this end we utilize the stochastic block model to study ensembles of infinitely large networks with arbitrary large-scale structures. We present results from numerical two-objective optimization simulations for networks with various fixed mean(More)
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