Sebastian Ullrich

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BACKGROUND AND STUDY AIMS A novel large-diameter, lumen-apposing, self-expanding metal stent with bilateral flanges was recently developed for endoscopic ultrasound (EUS)-guided transmural drainage of symptomatic pancreatic fluid collections (PFCs). The aim of this study was to evaluate the efficacy and safety of this stent in a large cohort. PATIENTS AND(More)
Palpation is a physical examination technique where objects, e.g., organs or body parts, are touched with fingers to determine their size, shape, consistency and location. Many medical procedures utilize palpation as a supplementary interaction technique and it can be therefore considered as an essential basic method. However, palpation is mostly neglected(More)
The grasping of virtual objects has been an active research field for several years. Solutions providing realistic grasping rely on special hardware or require time-consuming parameterizations. Therefore, we introduce a flexible grasping algorithm enabling grasping without computational complex physics. Objects can be grasped and manipulated with multiple(More)
In this paper we propose a software-based approach to simulate the haptics of the human pulse. This effect can then be interactively explored by virtual palpation. The algorithm features a flexible, userdefined setup. In addition the simulation takes dynamic parameters into account and allows for many different use cases.
Sucrose esters have the potential to enhance both drug solubility and drug absorption. They are therefore alternatives to the widely used glycerides in the formulation of lipid-based drug delivery systems. A simple production of aqueous nanosized drug carrier systems consisting of amphiphilic sucrose fatty acid esters using exclusively nontoxic materials(More)
The analyses of previously generated Podospora anserina strains in which the mitochondrial superoxide dismutase, PaSOD3, is increased in abundance, revealed unexpected results, which, at first glance, are contradictory to the 'free radical theory of aging' (FRTA). To re-analyze these results, we performed additional experiments and developed a mathematical(More)
This paper describes an approach how to integrate virtual agents into the 3D multi-user online world Second Life. For this purpose we have implemented a new client software for Second Life that controls virtual agents (“bots”) and makes use of the Multimodal Presentation Markup Language 3D (MPML3D) to define their behavior. The technical merits and(More)
OBJECTIVES While remission is achieved in the majority of Wegener's granulomatosis (WG)-patients with cyclophosphamide, maintenance of remission remains a challenge due to the high rate of relapses. The purpose of this study was to evaluate the safety and efficacy of the combination of methotrexate (MTX) plus leflunomide (LEF) for the treatment of minor(More)
The main purpose is to provide an intuitive VR-based training environment for regional anesthesia (RA). The research question is how to process subject-specific datasets, organize them in a meaningful way and how to perform the simulation for peripheral regions. We propose a flexible virtual patient architecture and methods to process datasets. Image(More)
This paper describes an authoring language for specifying communicative behavior and interaction of agents in virtual worlds. We focus on the popular three-dimensional (3D) multi-user online world "Second Life" and the emerging "OpenSimulator" project. While tools for designing avatars and in-world objects exist, technology to support content creators in(More)