Sebastian Schroer

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AIMS/HYPOTHESIS Pancreatic beta cells undergo dynamic remodelling during the perinatal period, with enhanced neogenesis, proliferation and apoptosis observed. The molecular mechanisms responsible for these processes have yet to be elucidated. Survivin is an inhibitor of apoptosis, first described as being exclusively expressed in tumour and embryonic(More)
Pharmacokinetics were studied in relation to hepatic side-effects in 20 patients (19 adults aged 18-53 years and one child of 11 years) undergoing BMT after conditioning with 1 mg/kg busulfan (every 6 hours for 16 doses). Busulfan was quantitated in plasma samples at 10 time points within the 6 h dosing interval using HPLC before and after dose numbers 1,(More)
Very little objective data are available concerning the patient's perspective on clinical trial participation. Participants from the Asymptomatic Carotid Atherosclerosis Study and Clopidogrel vs. Aspirin in Patients at Risk for Ischemic Events Trial were personally interviewed by the nurse coordinator to document their views. A questionnaire including both(More)
Stroke and neurodegenerative diseases, among a range of other neurologic disorders, can cause chronic paralysis. Patients suffering from paralysis may remain unable to achieve even basic everyday tasks such as liquid intake. Currently, there is a great interest in developing robotic assistants controlled via brain-machine interfaces (BMIs) to restore the(More)
This study explores the ways in which clinical trial participation influences a person's health and health-promoting behaviors. Active study subjects with a minimum of 4 months' clinical trial participation were mailed a nurse-developed questionnaire. Seventy-three percent of the targeted group returned the survey by the deadline. The majority of(More)
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