Sebastian A. Markett

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The present case-control study investigated the processing of emotional pictures in excessive first-person-shooter-video-players and control persons. All participants of the fMRI experiment were confronted with pictures from four categories including pleasant, unpleasant, neutral content and pictures from the first-person-shooter-video-game 'Counterstrike'.(More)
AIMS To investigate the effects of actual and expected alcohol intake on the detection and interpretation of the basic emotions happiness and anger in facial expressions. METHODS n = 102 healthy participants performed a dynamic emotion recognition task before and after receiving a drink which contained either a moderate alcohol dose or no alcohol in a(More)
Primary headache and functional abdominal pain prevalences in an unselected populationbased sample of German preschool children and their parents (n=885) were collected in relation to health-related quality of life and sociodemographic variables. The pain symptoms were assessed according to IHS classification (2004) and Rome-II criteria (1999) during the(More)
Mounting evidence from animal studies show that the mesolimbic dopaminergic pathways are modulated by the brain-derived neurotrophic factor (BDNF). This study investigates in N=768 healthy Caucasian participants the influence of two prominent functional single-nucleotide polymorphisms (SNPs) on the BDNF gene (BDNF Val66Met SNP) and the ankyrin repeat and(More)
Perspective-taking has become a main focus of studies on moral judgments. Recent fMRI studies have demonstrated that individual differences in brain activation predict moral decision making. In particular, pharmacological studies highlighted the crucial role for the neuropeptide oxytocin in social behavior and emotional perception. In the present study(More)
Findings from twin studies yield heritability estimates of 0.50 for prosocial behaviours like empathy, cooperativeness and altruism. First molecular genetic studies underline the influence of polymorphisms located on genes coding for the receptors of the neuropeptides, oxytocin and vasopressin. However, the proportion of variance explained by these gene(More)
INTRODUCTION It has been hypothesized that two distinctive forms of Internet addiction exist. Here, generalized Internet addiction refers to the problematic use of the Internet covering a broad range of Internet-related activities. In contrast, specific forms of Internet addiction target the problematic use of distinct online activities such as excessive(More)
The temporal lobe plays a major role in anxiety and depression disorders and is also of importance for trait anxiety in the non-pathological range. The present study investigates self-report data of personality dimensions linked to trait anxiety in the context of white matter tract integrity in the temporal lobes of the human brain in a large sample of(More)
The emotion of anxiety represents one of the most studied topics in the neurosciences, in part due to its relevance for understanding the evolutionary development of the human brain and its role in the pathogenesis of psychopathological conditions. Structural magnetic resonance imaging (sMRI) has enabled mapping of the anxious human brain and has(More)
Knock-out studies in mice suggest a role of the CHRNA4 gene in anxiety. In the present study we extend this finding to humans by means of a genetic association study. In a sample of N = 574 healthy White participants, the CHRNA4 rs1044396 polymorphism is related to the common variance of several conceptualizations of negative emotionality. Compared to(More)