Sebastiaan van-Liempd

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Cell-derived extracellular vesicles (EVs) are involved in the development of different pathologies including inflammatory diseases and cancer (1) and have demonstrated a promising potential for human diagnostic (2) and therapeutic applications (3). Constitutive secretion of these vesicles has been described for platelets, reticulocytes, dendritic cells,(More)
Hepatocytes release extracellular vesicles (EVs) loaded with signaling molecules and enzymes into the bloodstream. Although the importance of EVs in the intercellular communication is already recognized, the metabolic impact of the enzymes carried by these vesicles is still unclear. We evaluated the global effect of the enzymatic activities of EVs by(More)
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