Sebastião David Santos-Filho

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The effect of acupuncture stimulation at Zusanli point (ST.36) on the bioavailability of radio-pharmaceutical 99mTc-sodium pertechnetate (Na99mTcO4) in Wistar rats was investigated. Ten healthy rats were allocated into two groups of five. Group 1 (n=5) was treated by acupuncture by inserting stainless steel needles bilaterally at ST.36; Group 2 was the(More)
The objective of this work was to investigate the effects of whole-body vibration on people with multiple sclerosis (MS). PubMed, CINAHL and Scopus databases were systematically searched for studies on the use of whole-body vibration (WBV) exercise in people with MS. These searches were supplemented with material identified in the references and in the(More)
Mentha crispa extract or 0.9% NaCl were (15 days) administered daily by gavage to Wistar rats. Animals then received Na99mTcO4 via ocular plexus and were sacrificed. Organs were isolated, radioactivity was determined, percentages of radioactivity in each organ was calculated, and statistical analyses performed. Significant (p = 0.0061) increases of(More)
The objective of this study is to investigate the differences of acupuncture effect between the Zusanli (St.36) and Sanyinjiao (SP.6) points on the gastrointestinal-tract (GIT) segment performed by the bioavailability of (99m)Tc-sodium-pertechnetate (Na(99m)TcO(4)) in rats. Male Wistar rats (n = 21) were allocated into three groups of seven each. Group 1(More)
Chrysobalanus icaco (abajeru; C.icaco) is recommended in the treatment of diabetes and other clinical disorders. Blood constituents labeled with technetium-99m (99mTc) are used in nuclear medicine. The aim of this study was to verify the effects of an abajeru extract on the labeling of blood constituents with 99mTc and on the shape of red blood cells (RBC).(More)
BACKGROUND Natural products might alter the labeling of blood constituents with technetium-99m ((99m)Tc) and these results may be correlated with modifications of the shape of the red blood cells (RBC). The biodistribution of radiopharmaceuticals can be also altered. OBJECTIVE This investigation aimed to determine biological effects of an aqueous extract(More)
PURPOSE The radionuclide bone scan is the basis of skeletal nuclear medicine imaging. Bone scintigraphy is a highly sensitive method for indicating disease in bone. Mechanical stimulation in the manner of whole-body vibration (WBV) appears beneficial to the maintenance and/or enhancement of skeletal mass in individuals. The aim of this work was to evaluate(More)
Radiopharmaceuticals are employed in patient diagnostics and disease treatments. Concerning the diagnosis aspect, technetium-99m (99mTc) is utilized to label radiopharmaceuticals for single photon computed emission tomography (SPECT) due to its physical and chemical characteristics. 99mTc fixation on pharmaceuticals depends on a reducing agent, stannous(More)
Aims: A stroke is a neurological disorder and muscle weakness is the most prominent impairment. Whole-body vibration (WBV) is a possible modality of exercise that is useful for improving physical capacity, bone mass, balance, proprioception and the quality of life in healthy subjects and in patients with several diseases and among them, the neurological(More)
We evaluated the in vitro effect of an aqueous extract of Ginkgo biloba (EGb) on the distribution in blood cells (BC) and plasma (P) and on the binding of Na(123)I to the blood constituents using precipitation with trichloroacetic acid. The radioactivity percentages insoluble (SF) and insoluble fraction (IF) of blood constituents were determined. The EGb(More)