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OBJECTIVE To investigate the associations between Parkinson's disease and other degenerative parkinsonian syndromes and environmental factors in five European countries. METHODS A case-control study of 959 prevalent cases of parkinsonism (767 with Parkinson's disease) and 1989 controls in Scotland, Italy, Sweden, Romania and Malta was carried out. Cases(More)
BACKGROUND Over half the world is exposed daily to the smoke from combustion of solid fuels. Chronic obstructive pulmonary disease (COPD) is one of the main contributors to the global burden of disease and can be caused by biomass smoke exposure. However, studies of biomass exposure and COPD show a wide range of effect sizes. The aim of this systematic(More)
The present birth cohort study investigated whether or not childhood wheeze and asthma are associated with parental exposure to occupational sensitisers that cause asthma. Parental occupation, from the Avon Longitudinal Study of Parents and Children (ALSPAC), was related to wheeze, asthma, ventilatory function, airway responsiveness and atopic sensitisation(More)
OBJECTIVE To compare levels of particulate matter, as a marker of secondhand smoke (SHS) levels, in pubs before and 2 months after the implementation of Scottish legislation to prohibit smoking in substantially enclosed public places. DESIGN Comparison of SHS levels before and after the legislation in a random selection of 41 pubs in 2 Scottish cities. (More)
  • S Semple
  • 2004
T he study of occupational and environmental exposure to chemicals has traditionally focussed on the quantity of dust, aerosol, or vapour inhaled. This has been driven by the high historic prevalence of respiratory illness among those in mining and manufacturing industries. The large proportion of respiratory physicians working in occupational medicine(More)
AIMS To measure particulate matter (PM) exposure of people involved in domestic work (i.e. housework by a resident, not paid work) in urban and rural Nepal, with exposure to biomass smoke in the rural areas, and to examine the performance of photometric devices in collecting these data. This paper details the results of these measurements and derives(More)
The discriminative power of existing dermal exposure models is limited. Most models only allow occupational hygienists to rank workers between and within workplaces according to broad bands of dermal exposure. No allowance is made for the work practices of different individuals. In this study a process-based, structured approach has been used to estimate(More)
OBJECTIVES This study examined whether it is possible to train occupational hygienists to estimate inhalation exposures reliably from limited occupational information using a new method and assessed improvements in the quality of the estimate using the aggregate from multiple assessors. METHODS Five occupational hygienists estimated inhalation exposure(More)
OBJECTIVES To examine changes in bar workers' exposure to second-hand smoke (SHS) over a 12-month period before and after the introduction of Scottish smoke-free legislation on the 26 March 2006. METHODS A total of 371 bar workers were recruited from 72 bars in three cities: Aberdeen, Glasgow, Edinburgh and small towns in two rural regions (Borders and(More)
Much is known about human exposure to workplace hazardous substances by inhalation and from skin contact, but there has been little systematic research into ingestion of hazardous substances used at work. This review attempts to identify whether inadvertent ingestion of hazardous substances is an important route of exposure in the workplace and examines(More)