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Motor Cortex Embeds Muscle-like Commands in an Untangled Population Response
TLDR
We found that single motor cortex neurons displayed many muscle-like properties, but the structure of population activity was not muscle- like. Expand
Neural trajectories in the supplementary motor area and primary motor cortex exhibit distinct geometries, compatible with different classes of computation
TLDR
We consider the hypothesis that SMA guides movement by internally tracking contextual factors, and derive a prediction regarding the population trajectory geometry appropriate for that class of computations. Expand
Population activity structure of excitatory and inhibitory neurons
Many studies use population analysis approaches, such as dimensionality reduction, to characterize the activity of large groups of neurons. To date, these methods have treated each neuron equally,Expand
Neural Trajectories in the Supplementary Motor Area and Motor Cortex Exhibit Distinct Geometries, Compatible with Different Classes of Computation
TLDR
We examined neural activity in SMA and primary motor cortex (M1) as monkeys cycled various distances through a virtual environment. Expand
Interrogating theoretical models of neural computation with emergent property inference
TLDR
A cornerstone of theoretical neuroscience is the circuit model: a system of equations that captures a hypothesized neural mechanism. Expand
Approximating exponential family models (not single distributions) with a two-network architecture
TLDR
We introduce a two-network architecture and optimization procedure for learning intractable exponential family models (not a single distribution from those models). Expand
Fast algorithm for neural network reconstruction
TLDR
We propose an efficient and accurate way of predicting the connectivity of neural networks in the brain represented by simulated calcium fluorescence data. Expand