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BACKGROUND Deposition of beta-amyloid in the brains of patients with Alzheimer's disease is thought to precede a chain of events that leads to an inflammatory response by the brain. We postulated that genetic variation in the regulatory region of the gene for the proinflammatory cytokine tumour necrosis factor alpha (TNF-alpha) leads to increased risk of(More)
The concept of statistical literacy needs to be refreshed, regularly. Major changes in the ways that data can be accessed from government and non-government agencies (the 'semantic web') allow everyone to access huge databases, to create new variables, and to explore new relationships. New ways of visualising data provide further challenges and(More)
This paper explores the differences between boys and girls in their approach to ICT. Data were gathered from students in the final grades of high school in the Swiss Canton Ticino as part of a wider European project, with a particular focus on the potential uptake of a study or professional career in ICT. Preliminary focus groups with teachers and(More)
Computers facilitate reasoning with complex data. We report a study where 195 students aged 12 to 15 years were presented with computer based tasks that require reasoning with multivariate data, together with paper based tasks from a well established scale of statistical literacy. All the tasks fitted well onto a single Rasch scale; computer tasks were(More)
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