Sean Marrett
Functional MRI Facility, NIMH, NIH. USA Bethesda, MD 20892-1148
- Publications
- Influence
A unified statistical approach for determining significant signals in images of cerebral activation.
We present a unified statistical theory for assessing the significance of apparent signal observed in noisy difference images. The results are usable in a wide range of applications, including fMRI,… Continue Reading
Journal of cerebral blood flow and metabolism…
Many studies of brain function with positron emission tomography (PET) involve the interpretation of a subtracted PET image, usually the difference between two images under baseline and stimulation… Continue Reading
The relationship between blood oxygenation level-dependent (BOLD) MRI signals, cerebral blood flow (CBF), and oxygen consumption (CMR(O2)) in the physiological steady state was investigated. A… Continue Reading
Findings from single-cell recording studies suggest that a comparison of the outputs of different pools of selectively tuned lower-level sensory neurons may be a general mechanism by which… Continue Reading
Proceedings of the National Academy of Sciences…
The aim of this study was to test the hypothesis that, within a specific cortical unit, fractional changes in cerebral blood flow (CBF) and cerebral metabolic rate of oxygen consumption (CMR(O(2)))… Continue Reading
Perceptual decision making is the act of choosing one option or course of action from a set of alternatives on the basis of available sensory evidence. Thus, when we make such decisions, sensory… Continue Reading
We used high-field (3T) functional magnetic resonance imaging (fMRI) to label cortical activity due to visual spatial attention, relative to flattened cortical maps of the retinotopy and visual areas… Continue Reading
The representation of pain in the cerebral cortex is less well understood than that of any other sensory system. However, with the use of magnetic resonance imaging and positron emission tomography… Continue Reading
Proceedings of the National Academy of Sciences…
Perceptual decision making typically entails the processing of sensory signals, the formation of a decision, and the planning and execution of a motor response. Although recent studies in monkeys and… Continue Reading
PET images of cerebral blood flow (CBF) in an activation study are usually smoothed to a resolution much poorer than the intrinsic resolution of the PET camera. This is done to reduce noise and to… Continue Reading