Sean M Moran

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Androcam replaces calmodulin as a tissue-specific myosin VI light chain on the actin cones that mediate D. melanogaster spermatid individualization. We show that the androcam structure and its binding to the myosin VI structural (Insert 2) and regulatory (IQ) light chain sites are distinct from those of calmodulin and provide a basis for specialized myosin(More)
The degree to which behaviour, vertical movement and horizontal transport, in relation to local hydrodynamics, may facilitate secondary dispersal in the water column was studied in post-larval Sillaginodes punctata in Port Phillip Bay, Australia. S. punctata were captured in shallow seagrass beds and released at the surface in three depth zones (1.5, 3 and(More)
We present new results from our comprehensive comparative survey of two massive, intermediate redshift galaxy clusters, Cl 0024 + 17 (z = 0.39) and MS 0451 − 03 (z = 0.54). Combining HST optical and GALEX UV imaging with Keck spectroscopy of member galaxies, we identify and study several key classes of 'transition objects' whose stellar populations or(More)
BACKGROUND Sequence variation in the human 12/15 lipoxygenase (ALOX15) has been associated with atherosclerotic disease. We functionally characterized an ALOX15 promoter polymorphism, rs2255888, previously associated with carotid plaque burden. METHODOLOGY/PRINCIPAL FINDINGS We demonstrate specific in vitro and in vivo binding of the cytoskeletal protein,(More)
We measure the morphology–density relation of galaxies at z=1 across the full three orders of magnitude in projected galaxy density available in low–redshift studies. Our study adopts techniques that are comparable with those applied at lower redshifts, allowing a direct investigation of how the morphological segregation of galaxies has evolved over the(More)
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