Sean M Ferrell

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PURPOSE We evaluated ejaculatory response and semen quality in 653 trials of penile vibratory stimulation in 211 men with spinal cord injury, and compared results with low versus high amplitude vibratory stimulation. MATERIALS AND METHODS Low and/or high amplitude penile vibratory stimulation was performed 1 to 27 times in each patient, and antegrade and(More)
Few studies have quantified lower limb muscle activity over 24 h using electromyographic signals (EMG). None have described the changes in EMG duration and intensity when data are analyzed with different thresholds. Continuous bilateral EMG recordings were made from vastus lateralis (VL) in 10 subjects (20-48 yr) for 24 h. Before and after this recording,(More)
The semen of most men with spinal cord injury (SCI) contains sperm with abnormally low motility. Studies suggest that the seminal plasma is the source of this condition. The seminal plasma of men with SCI contains an abnormally high number of white blood cells (WBC), specifically, activated T cells. It is known that activated T cells secrete cytokines and(More)
PURPOSE Recent evidence suggests that the seminal plasma of spinal cord injured men contributes to their distinctive semen profile of normal sperm concentration but low sperm motility and viability. This finding indicates that sperm in these men may be normal before exposure to the seminal and prostatic fluids. To investigate this question we compared vas(More)
PURPOSE Based on the findings of a previous study of pressure differentials in the external and internal urinary sphincters during electroejaculation we determined whether semen retrieval in men with spinal cord injury would be improved by interrupting current delivery during electroejaculation. MATERIALS AND METHODS We tested continuous versus(More)
OBJECTIVE To evaluate the role of parenchyma-sparing surgery in patients with renal cell carcinoma (RCC). PATIENTS AND METHODS Between 1965 and 1990, 34 patients with RCC underwent renal parenchyma-sparing surgery. There were 22 men and 12 women with a mean age of 62 years (range 40-89). Ten patients underwent enucleation (Group A), 15 partial nephrectomy(More)
The semen of most men with spinal cord injury (SCI) contains an abundance of leukocytes. It is not known if this leukocytospermia contributes to the abnormally low sperm motility observed in many of these men. Our study used flow cytometry to identify the leukocyte population in the semen of 12 men with SCI compared to 8 healthy age-matched control(More)
PURPOSE Recent investigations have indicated that factors within the seminal plasma may contribute to the condition of low sperm motility in men with spinal cord injury. To determine whether the prostate gland functions normally in these men we chose prostate specific antigen (PSA) as a marker of prostatic function, and compared serum and semen(More)
STUDY DESIGN Retrospective chart review. OBJECTIVE To identify factors in addition to level of injury (LOI) that may predict ejaculation by penile vibratory stimulation (PVS) in spinal cord injured males. SETTING Major urban medical school and teaching hospital. MATERIALS AND METHODS Presence of a bulbocavernosus response (BCR) and a hip flexor(More)
OBJECTIVE To determine if semen quality of men with spinal cord injury (SCI) undergoes a progressive decline as a function of years postinjury. DESIGN A retrospective analysis of cross-sectional data. SETTING University-based research center. SUBJECTS Semen quality was examined in 638 specimens from 125 men with SCI. INTERVENTION Penile vibratory(More)