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BACKGROUND Although the effect of maternal age on fertility is well known, it is unclear whether paternal age also affects fertility. This cross-sectional study sought to characterize the association between age and semen quality, a well-known proxy of fertility status. METHODS A convenience sample of 97 non-smoking men (aged 22-80 years) without known(More)
OBJECTIVE To review the literature on the association between male age and semen quality (semen volume, concentration, motility, and morphology) and fertility status (pregnancy rate and time to pregnancy/subfecundity). METHOD(S) Review of English language-published research over the last 20 years from January 1, 1980, through December 31, 1999, using(More)
Binaural responses of single neurons in the rat's central nucleus of the inferior colliculus (ICC) were recorded before and after local injection of excitatory amino acid receptor antagonists (either 1,2, 3,4-tetrahydro-6-nitro-2,3-dioxo-benzo[f]quinoxaline-7-sulfonamide disodium [NBQX], (+/-)-3-(2-carboxypiperazin-4-yl)-propyl-1-phosphonic acid [CPP],(More)
The contribution of the dorsal nucleus of the lateral lemniscus (DNLL) to binaural responses in the inferior colliculus of the rat was determined for a wide range of interaural time differences (ITDs). Single-unit action potentials were recorded from the inferior colliculus before and after local injection of the excitatory amino acid antagonist kynurenic(More)
Cognitive remediation (CR) is a treatment approach that is being increasingly examined as a means through which the cognitive impacts of schizophrenia might be ameliorated. While CR has demonstrated good outcomes when paired with supported employment, little is known regarding how it might be integrated within supported education contexts. In this study CR(More)
With increasing availability of drugs for impotence and advanced reproductive technologies for the treatment of subfertility, more men are fathering children at advanced ages. We conducted a study of the chromosomal content of sperm of healthy men aged 24-57 years to (a) determine whether father's age was associated with increasing frequencies of aneuploid(More)
Extracellular recordings were made with microelectrodes from single neurons in the rat's dorsal nucleus of the lateral lemniscus (DNLL) and response characteristics were determined for monaural and binaural acoustic stimulation. The vast majority of DNLL neurons were narrowly tuned to sound frequency and their temporal responses to contralateral tone pulses(More)
BACKGROUND It is unclear whether frequency of sperm aneuploidy is associated with risk of fathering children with trisomy. METHODS We recruited 36 families with a boy with Klinefelter syndrome (KS), interviewed the fathers about their exposures and medical history, received a semen sample from each father, and collected blood samples from the mother,(More)
BACKGROUND We seek to determine whether dietary and supplement intake of specific micronutrients (zinc and folate) and antioxidants (vitamins C, E and beta-carotene) is associated with semen quality. METHODS Ninety-seven healthy, non-smoking men provided semen and were interviewed. Average daily nutrient intake from food and supplements was derived from a(More)
This study examined the protective role of self-esteem, social involvement, and secure attachment among homeless youths. These protective factors were examined as they ameliorate risks among 208 homeless youths surveyed in New York City and Toronto. Both mental and physical health indicators were employed in this study, including loneliness, feeling(More)