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We present data from a phase II study investigating a novel treatment strategy for relapsed/refractory mantle cell lymphoma (MCL). Twenty-six patients received lenalidomide 25 mg/d (days 1-21 of a 28-d cycle) for up to 6 cycles followed by low-dose maintenance lenalidomide (15 mg) in responding patients. Eight patients achieved complete or partial response(More)
Water is predicted to be among the most abundant (if not the most abundant) molecular species after hydrogen in the atmospheres of close-in extrasolar giant planets ('hot Jupiters'). Several attempts have been made to detect water on such planets, but have either failed to find compelling evidence for it or led to claims that should be taken with caution.(More)
The Infrared Array Camera (IRAC) is one of three focal plane instruments on the Spitzer Space Telescope. IRAC is a four-channel camera that obtains simultaneous broadband images at 3.6, 4.5, 5.8, and 8.0 m. Two nearly adjacent 5A2 ; 5A2 fields of view in the focal plane are viewed by the four channels in pairs (3.6 and 5.8 m; 4.5 and 8 m). All four detector(More)
Thermal images of cold dust in the Central Molecular Zone of the Milky Way, obtained with the far-infrared cameras on-board the Herschel satellite, reveal a ∼ 3 × 10 7 M ring of dense and cold clouds orbiting the Galactic Center. Using a simple toy-model, an elliptical shape having semi-major axes of 100 and 60 parsecs is deduced. The major axis of this(More)
One aim of modern astronomy is to detect temperate, Earth-like exoplanets that are well suited for atmospheric characterization. Recently, three Earth-sized planets were detected that transit (that is, pass in front of) a star with a mass just eight per cent that of the Sun, located 12 parsecs away. The transiting configuration of these planets, combined(More)
The hot Jupiter HD 189733b was observed during its primary transit using the Infrared Array Camera on the Spitzer Space Telescope. The transit depths were measured simultaneously at 3.6 and 5.8 m. Our analysis yields values of 2:356% AE 0:019% and 2:436% AE 0:020% at 3.6 and 5.8 m, respectively, for a uniform source. We estimated the contribution of the(More)
The hot Jupiter HD 209458b was observed during primary transit at 3.6, 4.5, 5.8 and 8.0 µm using the Infrared Array Camera (IRAC) on the Spitzer Space Telescope. We describe the procedures we adopted to correct for the systematic effects present in the IRAC data and the subsequent analysis. The light curves were fitted including limb-darkening effects and(More)