Sean CM Walsh

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OBJECTIVES In health technology assessment (HTA) agencies where cost-effectiveness plays a role in decision-making, an incremental cost-effectiveness ratio (ICER) threshold is often used to inform reimbursement decisions. The acceptance of submissions with ICERs higher than the threshold was assessed across different agencies and across indications, in(More)
evidence were extracted. Results: Our search identified 19 submissions, all of which included a placebo-controlled trial, and all except dimethyl fumarate also included a head-to-head trial against one of the beta-interferons but not any other therapies. Indirect comparisons against old and newer DMTs were also included in the submissions. Approximately 90%(More)
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