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Identification of regulators of the early stage of viral hemorrhagic septicemia virus infection during curcumin treatment.
Proteomics data suggest that curcumin pretreatment inhibits entry of VHSV in cells by downregulating FN1 or upregulating F-actin, while network analysis showed that HSC71 was the primary protein interacting with fibronectin (FN) 1, actins and gelsolin (GSN) in both V and CV samples and thus is a strong target candidate for the protection from V HSV infection at the viral entry stage.
Effectiveness of Periodic Treatment of Quercetin against Influenza A Virus H1N1 through Modulation of Protein Expression.
Kimchi, a traditional fermented food regularly consumed in Korea, contains various types of antimicrobial compounds. Among the tested compounds present in common spices used in Kimchi, quercetin
Detection of hepatitis A virus in seeded oyster digestive tissue by ricin A-linked magnetic separation combined with reverse transcription PCR.
Ricin A-linked magnetic bead separation combined with reverse transcription PCR can successfully detect HAV in artificially seeded oyster digestive tissue up to a 10(-4) dilution of the virus stock.
Integrated profiling of global metabolomic and transcriptomic responses to viral hemorrhagic septicemia virus infection in olive flounder
The results suggest that the suppression of ATP synthesis and antioxidant systems, such as glutathione and peroxisome signaling, could be the cause of necrosis, whereas the activation of the immune system could result in the inflammation of kidney tissue in VHSV‐infected olive flounder.
Modulation of proteome expression by F-type lectin during viral hemorrhagic septicemia virus infection in fathead minnow cells.
The results suggest RbFTL-3 modulates the expression of proteins related to viral budding (SNF8, CCT5 and TUBB) and thrombin signaling (F2) to increase the viability of VHSV infected cells.
Alginate oligosaccharide (AOS) improves immuno-metabolic systems by inhibiting STOML2 overexpression in high-fat-diet-induced obese zebrafish.
The results suggest that STOML2 can serve as a platform for further studies to discover novel treatments for metabolic disorders and suggest that AOS might be useful as a dietary health supplement, especially for reducing obesity.
Development of Lectin-Linked Immunomagnetic Separation for the Detection of Hepatitis A Virus
The findings demonstrate the feasibility of using SMS combined with RT-PCR to detect HAV at dilutions ranging from 10−1–10−4 of a HAV stock (titer: 104 TCID50/mL) and the binding of HAV to five lectins, including soybean agglutinin, was evaluated using ELISAs.
Rapid detection of norovirus from fresh lettuce using immunomagnetic separation and a quantum dots assay.
An immunomagnetic separation (IMS) and a quantum dots (QDs) assay is developed and results suggest that a fluorescence assay based on IMS and QDs is valid for detecting norovirus qualitatively according to fluorescent signal intensity within the same virus detection limit produced by IMS-RT-PCR and PEG-RT -PCR.
Comparison of bioactive compound contents and in vitro and ex vivo antioxidative activities between peel and flesh of pear (Pyrus pyrifolia Nakai)
We compared chemical constituents and antioxidative activities between the flesh and peel of two Asian pears (Pyrus pyrifolia Nakai cv. Niitaka and Chuhwangbae). Total phenolic, flavonoid, and
Application of Concanavalin A-Linked Magnetic Beads for the Detection of Hepatitis A Virus.
Con A-linked immunomagnetic separation combined with reverse transcriptase PCR, can detect HAV at a dilution concentration of 10-4 of the virus stock (titer: 104 median tissue culture infective dose per mL), indicating that Con A could be a promising candidate for concentrating HAV.